INTRODUCTION: Alzheimer's Disease (AD) is among the most prevalent neurodegenerative disorders globally, yet effective early diagnostic strategies remain lacking. Advances in multi-omics technologies and the integration of artificial intelligence int... read more
Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and Huntington's disease involve progressive neuronal dysfunction driven by mechanisms including protein aggregation, oxidative stress, mitoc... read more
This letter comments on the study by Turan et al., which evaluates the efficacy of large language models (LLMs) in predicting ICU admission needs. While commending the rigorous benchmark established for off-the-shelf LLMs, we propose methodological d... read more
The goal of this review is to trace the history of refractive correction, from the earliest optical devices to modern refractive surgical techniques. Following the invention of spectacles in the Middle Ages, the first corneal procedures, such as Sato... read more
Corneal neovascularization (CNV) is a frequent complication of many ocular surface diseases and represents a major threat to corneal transparency, visual function, and corneal graft survival. Accurate characterization, longitudinal monitoring, and as... read more
The discovery of antibiotics transformed modern medicine and extended the average human lifespan by decades. However, the initial golden era of antibiotic discovery has significantly waned, a decline aggravated by the relentless evolution of drug res... read more
BACKGROUND: Breast cancer-related lymphedema is a frequent and debilitating complication. Early identification of high-risk individuals is critical, yet conventional risk models rarely incorporate systemic inflammatory status. METHODS: In this prospe... read more
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental condition affecting mood, anxiety, learning, and sleep. Electroencephalogram (EEG) signals assist diagnosis, but challenges include complexity, nonlinearity, non-stationarity, ov... read more
INTRODUCTION: The advancement of AI-assisted oral disease diagnosis critically relies on the availability of annotated, high-quality datasets and resilient deep learning architectures. Nevertheless, progress in this domain has been impeded by the sca... read more
BACKGROUND: Coronal plane alignment of the knee (CPAK) categorizes knee phenotypes according to joint line obliquity (JLO) and the arithmetic hip‒knee‒ankle angle (aHKA). CPAK is traditionally measured via long leg radiographs, but recently other mod... read more
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