BACKGROUND: Adolescents with major depressive disorder (MDD) and bipolar disorder (BD) share substantial clinical overlap and elevated suicide risk, yet the neurobiological distinctions between these disorders and their associations with suicidality ... read more
Focal brain lesions from Acquired Brain Injuries (ABIs) present as regions of abnormal signal intensity on T1-weighted Magnetic Resonance Imaging (MRI) scans. These can disrupt automated neuroimaging processing algorithms traditionally developed on a... read more
OBJECTIVES: To keep pace with rapid medical innovation, health care must be organized to enable systematic learning from every patient. The 'outpatient innovation clinic' was established to support this goal. This paper presents 12 years of experienc... read more
AIMS: Obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) arise from impaired redox and energy homeostasis, yet current therapies remain limited. We evaluated the anti-obesity efficacy and mechanisms of Rhus verniciflua Stoke... read more
Artificial intelligence (AI) is advancing synthetic biology biosensors (SBBs), driving a fundamental shift from rational design to AI-driven prediction. This review establishes a systematic framework linking AI algorithms to the Design-Build-Test-Lea... read more
OBJECTIVE: To develop and validate a multi-lead electrocardiogram (ECG)-based machine learning system for automated classification of major psychiatric disorders (bipolar disorder, major depressive disorder, and schizophrenia) using cardiac autonomic... read more
Irregular clinical time series, composed of patient data from various physiological indicators, are essential for clinical decision-making. Effectively modeling these sequences for tasks like disease diagnosis and mortality prediction is a significan... read more
OBJECTIVE: Precision medicine applications depend on elucidating the underlying molecular mechanisms of disease. However, many disorders, such as endometriosis, remain poorly characterised genetically due to data scarcity, positive-unlabelled (PU) im... read more
Environmental pollution (Barking, Essex : 1987)
Mar 23, 2026
Microplastic pollution presents major environmental and health challenges, requiring accurate identification and quantification to assess its distribution and impact. Conventional methods such as chromatography and spectrometry provide precise result... read more
Environmental pollution (Barking, Essex : 1987)
Mar 23, 2026
Widespread ammonium (NH4+-N) contamination in groundwater, with local concentrations exceeding 20 mg/L, challenges traditional nitrogen removal, which is dominated by denitrification. Dissimilatory nitrate reduction to ammonium (DNRA), a nitrogen-ret... read more
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