AI Medical Compendium

The Genetics of TDP-43 Type C Neurodegeneration: A Whole-Genome Sequencing Study and Literature Review.

Neurology. Genetics Mar 23, 2026

BACKGROUND AND OBJECTIVES: Frontotemporal lobar degeneration TDP43 type C (TDP-C) is a rare and unique neurodegenerative disease that attacks the anterior temporal lobe. Recently, it was shown that Annexin-A11 and TDP-43 coaggregate specifically in T... read more

Clinical priors-inspired privileged knowledge distillation for reliable pancreatic lesion classification.

Medical image analysis Mar 23, 2026

Accurate classification of pancreatic lesions is critical for guiding treatment decisions, with computed tomography (CT) being the primary modality owing to its high spatial resolution. Although deep learning has advanced CT-based pancreatic lesion c... read more

Splitting-domain reformulation of symmetric strongly coupled four-spin NMR systems.

Journal of magnetic resonance (San Diego, Calif. : 1997) Mar 23, 2026

The analysis of strongly coupled 1H NMR spin systems of the AA'BB' and AA'XX' type has remained one of the most challenging problems in spectral interpretation for over six decades. The classical Pople framework provides a complete closed-form soluti... read more

Integrated in silico, in vitro, and machine learning pipeline for extraction of antioxidant peptides and lipids from fish viscera.

Food chemistry Mar 23, 2026

Fish viscera, a processing byproduct abundant in protein and oil, remains largely underutilized. This study aimed to develop a pipeline combining in silico, in vitro, and machine-learning strategies for rapid screening of antioxidant peptides from gr... read more

How ICU clinicians document 'Futility': A 10-year analysis of critical care notes using natural language processing notes.

Journal of critical care Mar 23, 2026

BACKGROUND: ICU patients frequently receive treatments clinicians perceive are futile which can cause conflict between clinicians, patients and families. Medical futility lacks a consensus definition, yet this ambiguous and contentious term is used i... read more

The impact of digitalization and energy transition policies on urban energy rebound effects in China: A double machine learning-based causal identification.

Journal of environmental management Mar 23, 2026

The digital economy has injected fresh momentum into China's growth, yet the accompanying energy rebound effect (ERE) deserves attention. This study measures the urban-level ERE in China from the technological progress perspective and treats the dual... read more

A zone-specific water quality modelling framework for medium and large lakes using interpretable machine learning.

Journal of environmental management Mar 23, 2026

The significant spatial heterogeneity of lake characteristics poses a persistent challenge for accurate prediction and effective management of medium and large lake water quality. In this study, we developed an interpretable machine learning (ML)-bas... read more

Comment on "Integrated multi-Omics and network toxicology elucidate the multi-target mechanisms of environmental hormones in driving hepatocellular carcinoma".

Ecotoxicology and environmental safety Mar 23, 2026

TCR recognition of peptide-HLA class II complexes in autoimmunity: Structural insights for therapeutic targeting.

Journal of autoimmunity Mar 23, 2026

Autoimmune diseases encompass a broad spectrum of disorders in which self-reactive T and B cells breach immune tolerance and drive chronic tissue inflammation. Although broad immunosuppressants and cytokine-targeted biologic therapies have improved d... read more

Unveiling the impact of employee-AI collaboration on help-seeking behavior among service employees in china: A social cognitive perspective.

Acta psychologica Mar 23, 2026

As employee-artificial intelligence (AI) collaboration becomes increasingly prevalent, understanding how it shapes employees' interpersonal dynamics has become imperative. Professional help-seeking, as an interpersonal behavior, plays a critical role... read more

Artificial Intelligence Medical Compendium