With the increasing frequency of extreme rainfall events due to climate change, enhancing flood resilience has become a critical focus for urban researchers and planners. However, existing studies rarely evaluate the relationship between flood resili... read more
Predictive maintenance (PdM) has seen significant advances through machine learning, yet its practical deployment remains challenged by data scarcity, system complexity, and uncertainty in cost-related decisions. The majority of current PdM strategie... read more
Artificial intelligence (AI) is increasingly explored for use in intensive care units. While most approved AI devices use narrow models, research is shifting towards generalist systems based on large language models and agentic AI. In this perspectiv... read more
Disorders of the central nervous system (CNS), neurological disorders, neurodegenerative disorders, genetic disorders) constitute a significant burden on global health, and current treatment options remain challenging. As treatment for CNS disorders ... read more
Biomedical engineers produce knowledge and artifacts. Across the life cycle of an idea, errors can creep in. In this letter, we propose the term linguistic, orthographic, and typographical errors in science (LOTS) to represent a category of errors th... read more
Therapeutic innovation & regulatory science
Mar 21, 2026
BACKGROUND: Traditional manual MedDRA coding in clinical data management (CDM) faces persistent challenges, including suboptimal site data quality, terminology complexity, low efficiency, inconsistent outcomes, frequent dictionary updates, and regula... read more
Accurate free energy simulations based on combined quantum mechanical and molecular mechanical (QM/MM) potentials are essential for understanding reaction mechanisms in complex environments. Achieving abĀ initio QM/MM accuracy at the cost of more affo... read more
Critical reviews in oncology/hematology
Mar 21, 2026
Ligand-receptor pair analysis, a key aspect of cell-to-cell interactions, is vital for understanding physiological and pathological processes in organisms. However, most analytical tools fail to incorporate spatial in situ information, resulting in f... read more
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