BACKGROUND: The exponential growth of electronic health records (EHRs), together with the recent entry into force of the European Health Data Space (EHDS) Regulation, highlights the urgent need for secure, interoperable environments that support the ... read more
OBJECTIVE: To evaluate the efficacy of a clinical decision support system (CDSS) on stroke care quality and clinical outcomes among patients with acute ischaemic stroke. DESIGN: Multicentre, cluster randomised clinical trial. SETTING: 77 hospitals ac... read more
Chronic obstructive pulmonary disease (COPD) is a leading cause of death with few effective therapies. While clinical staging distinguishes mild to very severe disease, recent molecular and single-cell studies have revealed that progression involves ... read more
Convolutional neural networks (CNNs) can estimate electrocardiogram (ECG)-based heart age. We compared three published CNNs in the Tromsø Study cohort (7,108 participants) for accuracy, agreement, and prognostic value. Mean absolute error versus chro... read more
Intraoperative cardiac arrhythmias present distinct characteristics compared to non-surgical environments, yet publicly available electrocardiogram (ECG) databases have primarily focused on ambulatory or intensive care environments. To address this g... read more
Solubility is a crucial property of organic compounds, impacting their potential applications in synthetic chemistry, materials science and drug design. Moreover, in technological processes mixtures of solvents are often utilized, making the solubili... read more
Heat stress severely compromises growth, reproduction, and yield in Solanum lycopersicum, necessitating the identification of reliable molecular biomarkers for thermotolerance. Here, we performed a comprehensive meta-analysis of transcriptomic datase... read more
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