Programmed death-ligand 1 (PD-L1) plays a central role in immune regulation in esophageal squamous cell carcinoma (ESCC) and has been widely used as a biomarker for immune checkpoint inhibitor therapy. However, the biological and clinical significanc... read more
AIMS: Diagnosing heart failure with preserved ejection fraction (HFpEF) remains challenging, particularly in older individuals. We hypothesized that machine learning (ML) approaches could improve diagnostic accuracy compared with HFpEF scores. METHOD... read more
International journal of neural systems
Mar 20, 2026
Inverse treatment planning is pivotal in tumor treatment planning. It enables the multi-objective optimization of radiation dose delivery, ensuring precise tumor targeting while sparing surrounding healthy tissues. This process often requires frequen... read more
Developmental medicine and child neurology
Mar 20, 2026
AIM: To describe how movement behaviours (sedentary time, light-intensity physical activity, moderate-to-vigorous physical activity [MVPA]) and parent-reported community physical activity participation vary across levels of environmental supportivene... read more
Journal of the American Heart Association
Mar 20, 2026
BACKGROUND: Stressor-associated atrial fibrillation (AF) refers to new-onset AF that occurs with a reversible, acute stressor. Identifying individuals at highest risk for AF recurrence is essential to guide management. Although clinical factors have ... read more
BACKGROUND: Spontaneous intracerebral hemorrhage (ICH) is associated with high mortality and disability. This study aimed to develop and validate machine learning models based on preoperative multimodal data to predict the risk of intraoperative rebl... read more
Microstructure control is critical for thermal barrier coating (TBC) performance, yet the complex, nonlinear process-structure relationships impede predictive design. Conventional data-driven approaches are limited by scarce experimental data and poo... read more
BACKGROUND: Epilepsy is a chronic neurological disorder marked by recurrent and apparently unpredictable seizures and associated with premature death, injury, and diminished quality of life. The unpredictability of seizures is a major concern for peo... read more
STUDY DESIGN: Retrospective longitudinal cohort study. OBJECTIVE: To identify postural strategies associated with improvement in gait speed following spinal fixation from thoracic vertebrae to pelvis using machine learning. SUMMARY OF BACKGROUND DATA... read more
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