Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 40,481 to 40,490 of 223,737 articles

Translating Histopathology Foundation Model Embeddings into Cellular and Molecular Features for Clinical Studies

bioRxiv Mar 19, 2026
AI-powered pathology foundation models provide general-purpose representations of histopathological images by encoding image tiles into numerical embeddings. However, these embeddings are not directly interpretable in biological or clinical terms and... read more 
bioinformatics

A Cross-Study Multi-Organ Cell Atlas ofMacaca fascicularis Informed by Human Foundation Model Annotation: A Resource for Translational Target Assessment

bioRxiv Mar 19, 2026
Non-human primates (NHPs), particularly Macaca fascicularis (cynomolgus macaque), represent an essential model for preclinical assessment of biologics due to their high genetic and physiological similarity to humans. However, mounting regulatory pres... read more 
bioinformatics

Cross-Modal Training Using Xenium Spatial Transcriptomics Enables DINO-DETR Based Detection of Vascular Niches in H&E Whole-Slide Images

bioRxiv Mar 19, 2026
Background: Tumor vasculature is a key driver of glioma progression, yet routine quantification depends on subjective histopathologic assessment or resource-intensive ancillary immunohistochemistry. A scalable, objective method for vascular phenotypi... read more 
pathology

Sequential narrative binding by hippocampal CA2/3 sustains lifespan episodic detail retrieval

bioRxiv Mar 19, 2026
Hippocampal subfield contributions to the structure of episodic memories across the lifespan remain incompletely understood, particularly regarding the mechanisms underlying sustained retrieval of detailed events regardless of age. Here, we show that... read more 
neuroscience

Semantic-Aware Energy-Efficient Operation inSmart Capsule Endoscopy

bioRxiv Mar 19, 2026
Goal-oriented semantic communication has recently emerged in wireless sensor-actuator networks, emphasizing the meaning and relevance of information over raw data delivery, thereby enabling resource-efficient telecommunication. This paradigm offers s... read more 
bioinformatics

ABAG-Rank: Improving Model Selection of AlphaFold Antibody-Antigen Complexes by Learning to Rank

bioRxiv Mar 19, 2026
Motivation: AlphaFold has transformed structural biology with an unprecedented accuracy in modeling protein structures and their interactions with biomolecules, with AlphaFold3 (AF3) achieving state-of-the-art performance. However, AF3 and other meth... read more 
bioinformatics

The first step is not always the hardest: A change-point analysis of predictive learning

bioRxiv Mar 19, 2026
The progress of learning is usually quantified by averaging responses across participants and/or multiple trials within a block. However, such approaches obscure the trial-by-trial progress of learning, which has been shown recently to express a rich... read more 
neuroscience

Spatio-temporal mapping of immune cell dynamics during human sequential lymph node metastasis

bioRxiv Mar 19, 2026
Regional lymph node (LN) metastasis critically influences distant metastatic progression, anti-tumour immunity, and patient prognosis. While tumour-induced immune modulation in tumour-draining LNs (TDLNs) has been extensively studied using murine mod... read more 
immunology

Enabling high-plex spectral imaging via DNA-barcoded signal tuning and panel optimization

bioRxiv Mar 19, 2026
High-plex spectral imaging has the potential to transform the analysis of spatial organization in cells and tissues, yet its practical implementation remains limited by challenges in panel design, sample preparation, signal balancing, and experimenta... read more 
bioengineering

A genetically encoded local learning rule enables physical learning in engineered bacteria

bioRxiv Mar 19, 2026
Training physical neural networks directly in matter remains difficult because most platforms do not implement weight storage and weight update within the same physical substrate. Here we show that engineered Escherichia coli can implement a genetica... read more 
synthetic biology
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