The basic computational unit of the brain has long been defined as the neuron. However, mounting evidence suggests that other cells, especially astrocytes, also perform computations. Here, we demonstrate that cerebellar astrocytes decompose norepinep... read more
The proliferation of high-dimensional data in ecology and evolutionary biology raises the promise of statistical and machine learning models that are highly predictive and interpretable. However, high-dimensional data are commonly burdened with an in... read more
Rapid behavioral adaptation requires the brain to solve a fundamental computational dilemma: how to flexibly update learned rules while maintaining stable motor performance. This flexibility-stability trade-off is central to cognitive function and ar... read more
Background: Advances in medicine depend on analyzing large and complex data sources, but discovery is partly constrained by the limited time and domain expertise of human researchers. Agentic artificial intelligence (agentic AI) can accelerate discov... read more
Background Snakebite envenoming is a significant global health crisis that has been long neglected as a global health priority. It is a huge problem for rural communities of low and middle-income countries, India accounts for the largest proportion o... read more
Stroke is a leading cause of mortality and morbidity worldwide. MRI-visible perivascular spaces (PVS) are an emerging marker of cerebral small vessel disease and may have prognostic value in stroke. We investigated longitudinal changes in PVS volume ... read more
Obstructive sleep apnoea (OSA) is a disorder marked by repeated episodes of airway collapse during sleep, leading to hypoxaemia and sympathoexcitation. Its impact on brain fluid transport remains unclear. We investigated MRI-visible perivascular spac... read more
Atrial fibrillation and heart failure impose substantial health burdens worldwide, yet existing prediction models lack sufficient accuracy and generalizability. We developed CARDIAC-FM, a multimodal foundation model that learns joint representations ... read more
Cardiovascular disease is one of the leading causes of death worldwide, with myocardial infarction (MI) being a major cause of both morbidity and mortality among cardiovascular patients. MI Patients face a higher risk of cardiovascular disease recurr... read more
Background: Length of stay (LOS) is a critical metric for hospital operational efficiency. While structured clinical data is widely used to predict LOS, unstructured admission notes contain latent prognostic information regarding diagnostic uncertain... read more
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