Early diagnosis of lung cancer is challenging due to biological uncertainty and the limited understanding of the biological mechanisms driving nodule progression. To address this, we propose Nodule-Aligned Multimodal (Latent) Diffusion (NAMD), a nove... read more
Applying machine learning to sensitive time-series data is often bottlenecked by the iteration loop: Performance depends strongly on preprocessing and architecture, yet training often has to run on-premise under strict data-local constraints. This is... read more
Automated diagnosis from chest computed tomography (CT) scans faces two persistent challenges in clinical deployment: distribution shift across acquisition sites and performance disparity across demographic subgroups. We address both simultaneously a... read more
Histopathology foundation models (HFMs), pretrained on large-scale cancer datasets, have advanced computational pathology. However, their applicability to non-cancerous chronic kidney disease remains underexplored, despite coexistence of renal pathol... read more
Deep learning has achieved remarkable success in medical image analysis, yet its performance remains highly sensitive to the heterogeneity of clinical data. Differences in imaging hardware, staining protocols, and acquisition conditions produce subst... read more
Dysarthric speech quality assessment (DSQA) is critical for clinical diagnostics and inclusive speech technologies. However, subjective evaluation is costly and difficult to scale, and the scarcity of labeled data limits robust objective modeling. To... read more
Radiology report annotation is essential for clinical NLP, yet manual labeling is slow and costly. We present RadAnnotate, an LLM-based framework that studies retrieval-augmented synthetic reports and confidence-based selective automation to reduce e... read more
Single-cell RNA sequencing (scRNA-seq) has become a cornerstone experimental technique in tissue biology, with gene expression data for over 100 million cells available in public repositories. The high dimensionality, sparsity, and technical noise in... read more
The diverse regulatory functions, protein production capacity, and stability of natural and synthetic RNAs are closely tied to their ability to fold into intricate structures. Determining RNA structure is thus fundamental to RNA biology and bioengine... read more
UNLABELLED: Perineural invasion (PNI) is an important pathologic feature of cervical cancer that is associated with poor prognosis and provides key information for clinical decisions. A better understanding of the molecular mechanisms underlying PNI ... read more
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