Falls among older adults can result in hip fractures that requires x-ray based assessment at emergency department (ED). Only 25.7% of patients presenting to EDs are diagnosed with a hip fracture, as such improved diagnosis prior to transportation to ... read more
Machine learning approaches are increasingly applied to high-dimensional biological data in which features are often dataset-dependent. In many omics workflows, features are computed using information derived from the entire dataset, such as correlat... read more
Real-time tracking and automated response systems are essential for standardising experiments, reducing observer bias, and improving reproducibility in studies of movement and behaviour. However, existing solutions face significant challenges: AI-bas... read more
Virtual cell modeling is currently hindered by a "data-utility paradox": biological information is fragmented between context-rich clinical RNA-seq and perturbation-dense experimental assays, leading to poor predictive generalization in human context... read more
Motivation: Protein complexes are central to cellular function, but experimental determination of their structures remains challenging. Structure prediction methods require prior knowledge of stoichiometry - the number of copies of each protein entit... read more
The growing threat of antimicrobial resistance underscores the demand for new therapeutic modalities. Phage lysins are promising candidates, yet their large-scale discovery from expanding genomic resources remains limited. Existing computational meth... read more
Synthetic data generation is a promising approach for biomedical data sharing and dataset augmentation, yet existing methods lack mechanisms to preserve statistical properties necessary for scientific analysis. To address this, we introduce RLSYN+REG... read more
Purpose: To evaluate the performance of machine learning models for automated glaucoma detection using multimodal clinical, structural, and functional data from a West African clinical cohort. Methods: In this retrospective observational study, we an... read more
Mental health related problems in adolescents are not always properly evaluated because of incomplete evaluation methods that do not combine biological, behavioral, and demographic details. Therefore, our study proposes a twin-aware multimodal deep l... read more
Background: Anemia is nearly ubiquitous in hospitalized patients with congestive heart failure (CHF), yet little data informs the decision to transfuse blood in this population. Objectives: To determine average and heterogenous effects of blood trans... read more
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