Dementia, a progressively debilitating neurodegenerative disorder, poses a growing challenge to global healthcare due to its subtle early onset and lack of accurate temporal diagnostic models. Traditional machine learning (ML) approaches for dementia... read more
A Bayesian optimization-based design framework for Tuned Inerter Dampers (TIDs) is presented in this paper. The TIDs are used to high-rise base-isolated buildings that are subjected to ground motions that are far-fault, near-fault non-pulse, and near... read more
Restful sleep is essential for health, yet many children with Attention Deficit Hyperactivity Disorder (ADHD) experience disturbances such as delayed sleep onset, shorter total sleep time, frequent awakenings, and daytime fatigue. Accurate detection ... read more
Early identification of patients with Alzheimer's disease (AD) who will experience near-term cognitive decline can support trial enrichment and risk-stratified follow-up. Using the Alzheimer's Disease Neuroimaging Initiative (ADNI), we developed two ... read more
Predicting drug-target binding remains a central challenge in computational drug discovery, particularly due to the need for models that jointly capture molecular topology, chemical substructures, and protein sequence dependencies. We propose MSCMF-D... read more
Physical activity and mobility are critical for healthy aging and predict diverse health outcomes. While wrist-worn accelerometers are widely used to monitor physical activity, estimating gait metrics from wrist data remains challenging. We extend El... read more
BACKGROUND: Deep learning faces a significant bottleneck in medical image analysis due to its reliance on large-scale, expert-annotated datasets. This challenge is acute in ophthalmology, particularly for detecting early-stage diseases like mild Diab... read more
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