AI Medical Compendium

Simulated Patient Queries Reveal Limitations of ChatGPT in Dermatologic Image Classification.

International journal of dermatology Mar 11, 2026

A practical framework for clone selection, media-feed screening, and upstream process parameter optimization for a mAb CHO cell culture process.

Biotechnology progress Mar 11, 2026

This study presents a data-driven workflow for upstream process development in biologics manufacturing, aimed at improving consistency, efficiency, and decision-making using established statistical and machine learning tools. Rather than relying on s... read more

Parametrized Quantum Circuit Learning for Quantum Chemical Applications.

Journal of chemical information and modeling Mar 11, 2026

In the field of quantum machine learning (QML), parametrized quantum circuits (PQCs)─constructed using a combination of fixed and tunable quantum gates─provide a promising hybrid framework for tackling complex machine learning problems. Despite numer... read more

Exploring the mechanism of polymorphonuclear neutrophils against sepsis based on immune model.

Annals of medicine Mar 11, 2026

BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and remains a major global health challenge. Polymorphonuclear neutrophils (PMNs), as major effectors of innate immunity, are essential for... read more

Improvement of Peak Integration in Capillary Electrophoresis: Reference Data Set No. 1.

Electrophoresis Mar 11, 2026

Capillary electrophoresis (CE) often provides superior separation of macromolecules such as monoclonal antibodies (mAbs), a major biopharmaceutical class, compared with liquid chromatography. However, electropherograms frequently exhibit complex base... read more

Guiding Preventive Care Strategies for Patients With Atherosclerotic Plaque on Coronary CTA: Primary Outcomes of the DECIDE Registry.

JACC. Cardiovascular imaging Mar 11, 2026

BACKGROUND: Artificial intelligence-enabled coronary plaque analysis (AI-CPA) has been shown to improve cardiovascular risk prediction. However, little is known about how these measures influence management. OBJECTIVES: This study sought to define ch... read more

ROPE: a novel method for real-time phase estimation of complex biological rhythms.

Journal of the Royal Society, Interface Mar 11, 2026

Accurate phase estimation-the process of assigning phase values between 0 and 2π to repetitive or periodic signals-is a cornerstone in the analysis of oscillatory signals across diverse fields, from neuroscience to robotics, where it is fundamental, ... read more

Influence of behavioural contingency on developmental song learning in young zebra finches (Taeniopygia guttata) tutored by a robot bird.

Proceedings. Biological sciences Mar 11, 2026

In humans and other animals, social robots can serve as effective tutors for learning new skills. Young oscines learn their song by imitating conspecific adults. In a previous study, we demonstrated that a robotic bird can be as effective as a live t... read more

Spatiotemporal clustering of state-level opioid, opioid-stimulant, and opioid-benzodiazepine polysubstance deaths across the U.S.: Hierarchical agglomerative clustering analysis.

Drug and alcohol dependence Mar 11, 2026

BACKGROUND: Polysubstance use continues to complicate the US overdose landscape, with over 107,000 lives lost to drug overdoses in 2022. The present study uses hierarchical agglomerative clustering to identify distinct spatiotemporal profiles of opio... read more

Protein language model-guided generative design of affinity peptides for chromatographic purification of lentiviral vectors.

Journal of chromatography. A Mar 11, 2026

Lentiviral vectors (LVs) have emerged as the most promising tool for cell and gene therapy. However, LVs are very fragile and sensitive to shear stress, buffer pH and salt concentration, resulting in serious hurdles in downstream processing. To addre... read more

Artificial Intelligence Medical Compendium