BACKGROUND AND AIMS: To identify novel biomarkers and therapeutic targets for polycystic ovary syndrome (PCOS) using integrated bioinformatics approaches. METHODS: We integrated two microarray datasets (GSE34526, nā=ā10; GSE137684, nā=ā12) and valida... read more
Multiple sclerosis (Houndmills, Basingstoke, England)
Mar 6, 2026
OBJECTIVES: Robust automated classification of paramagnetic rim lesions (PRLs) and remyelinated lesions based on iron and myelin content in people with multiple sclerosis (pwMS). MATERIALS AND METHODS: In this prospective study (2018-2022), three-dim... read more
Advanced materials (Deerfield Beach, Fla.)
Mar 6, 2026
Acoustic transducers are essential for object localization and environmental sensing. Conventional transducers rely on piezoelectric crystals, whose acoustic-electric response is fixed by the crystal lattice's inherent asymmetry and orientation. This... read more
INTRODUCTION: Emergency department crowding and increasing patient complexity challenge traditional triage models. Artificial intelligence may support triage decision making, but nurses' perceptions shape real-world adoption. METHODS: We conducted a ... read more
Ecotoxicology and environmental safety
Mar 6, 2026
Nitenpyram (NIT) is an insecticide used primarily for flea control in pets, especially cats and dogs. Some studies suggest that NIT is associated with cancer development, but the mechanisms involved are unclear. In this study, we integrated multi-pla... read more
Journal of epidemiology and population health
Mar 6, 2026
Chronic kidney disease (CKD) represents a heavy global health burden associated with increased mortality and morbidity and high economic impact. Chronic kidney disease, which is largely asymptomatic and is diagnosed based on laboratory tests, is part... read more
Dimensionality reduction methods are widely used in neuroscience to investigate two complementary aspects of neural activity: the distribution of single-neuron functional properties and the low-dimensional collective dynamics of population activity. ... read more
Advanced differentiated thyroid cancer (DTC) is characterized by limited therapeutic options and unfavorable prognosis. To address this, we conduct proteogenomic analysis of 113 advanced DTCs, identifying three molecularly distinct subtypes: canonica... read more
Reliable prediction and interpretation of water quality dynamics are essential for environmental monitoring and risk-informed water resources management. Explainable machine learning (XML) offers means to interpret complex predictive models; however,... read more
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