Molecular dynamics (MD) simulations provide detailed insights into biomolecular motion but are often limited by the prohibitive cost of sampling long-timescale behavior. Here, we present a Transformer-based framework that reconstructs temporally cont... read more
The prediction of protein-protein interactions is central to structural biology, yet leading models are often computationally expensive, creating an accessibility gap for many high-throughput applications. Furthermore, common evaluation metrics such ... read more
DNA extracted from tissue samples typically derive from of a complex mixture of cell types. Without single cell analysis, it has been generally impossible to determine the cell type of origin for most molecules. One clear example of this is in the co... read more
Resistance to systemic therapy is a major unmet challenge in pancreatic cancer. To identify potential mechanisms of resistance, we developed a novel 3D pipeline in clinical samples that uses deep learning to classify sensitive and persistent tumor ce... read more
Sense of agency (SoA), the experience of controlling one's actions and their consequences, is crucial for self-representation and adaptive goal-directed behavior. Classic comparator models explain SoA as the match between predicted and actual sensori... read more
Accurate predictions of the interactions (covalent bonds and non-covalent contacts between atoms) in a molecular system require scalable, accurate, and interpretable energy functions. While classical force fields and knowledge-based energy functions ... read more
Diet plays a critical role in human health, with growing evidence linking dietary habits to disease outcomes. However, extracting structured dietary knowledge from biomedical literature remains challenging due to the lack of dedicated relation extrac... read more
Spatially resolved omics technologies reveal tissue organization at single-cell resolution but remain limited by the cost of the assays, incomplete spatial coverage, 2D-only imaging, and experimental artifacts. These factors motivate the need for \te... read more
Chemical risk assessment for insects relies largely on mortality endpoints in a few model species, limiting detection of ecologically relevant sublethal effects and cross-taxon comparisons. Behaviour is a sensitive indicator of neurotoxic stress, but... read more
Quantifying task difficulty remains an open theoretical problem in neuroscience and artificial intelligence. While difficulty is often treated as a scalar property of stimuli or optimization landscapes, neural computation unfolds as a transient recon... read more
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