Chimeric antigen receptor (CAR) T-cell therapy has transformed the management of hematologic malignancies, achieving high remission rates in relapsed or refractory B-cell acute lymphoblastic leukemia, large B-cell lymphoma, and multiple myeloma. By r... read more
Engineered CRISPR gene drives are a promising new strategy for fighting malaria and other vector-borne diseases. One useful approach to predict the outcome of a drive release is individual-based modeling, allowing simulation of the chasing phenomenon... read more
Federated learning (FL) faces two structural tensions: gradient sharing enables data-reconstruction attacks, while non-IID client distributions degrade aggregation quality. We introduce PTOPOFL, a framework that addresses both challenges simultaneous... read more
Evaluation of AI systems often requires synthetic test cases, particularly for rare or safety-critical conditions that are difficult to observe in operational data. Generative AI offers a promising approach for producing such data through controllabl... read more
Deep learning in cardiac MRI (CMR) is fundamentally constrained by both data scarcity and privacy regulations. This study systematically benchmarks three generative architectures: Denoising Diffusion Probabilistic Models (DDPM), Latent Diffusion Mode... read more
Attributing authorship to paintings is a historically complex task, and one of its main challenges is the limited availability of real artworks for training computational models. This study investigates whether synthetic images, generated through Dre... read more
Large-scale Vision-Language Foundation Models (VLFMs), such as CLIP, now underpin a wide range of computer vision research and applications. VLFMs are often adapted to various domain-specific tasks. However, VLFM performance on novel, specialised, or... read more
Pathology report generation remains a relatively under-explored downstream task, primarily due to the gigapixel scale and complex morphological heterogeneity of Whole Slide Images (WSIs). Existing pathology report generation frameworks typically empl... read more
We introduce Helios, the first 14B video generation model that runs at 19.5 FPS on a single NVIDIA H100 GPU and supports minute-scale generation while matching the quality of a strong baseline. We make breakthroughs along three key dimensions: (1) ro... read more
Feed-forward transformer models have driven rapid progress in 3D vision, but state-of-the-art methods such as VGGT and $π^3$ have a computational cost that scales quadratically with the number of input images, making them inefficient when applied to ... read more
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