Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 45,041 to 45,050 of 224,055 articles

A screen for stress-induced sleep genes in C. elegans reveals a role for glutamate signaling

bioRxiv
Sleep is an essential behavioral state that evolved early in animals, possibly with the advent of the nervous system. The complexity of sleep neural networks varies significantly across phylogeny, yet common signaling molecules exist. Stress-induced ... read more 

Faster science, penalties in evaluation, and concerns on quality and impact: Researchers' use and perceptions of preprints

bioRxiv
The preprint ecosystem has expanded rapidly over the past decade, fundamentally altering science communication. Yet, the scholarly community's attitudes toward this shift remain underexplored. Through a large-scale survey of US and Canadian biomedica... read more 

Ligand-guided Sequence-structure Co-design of De Novo Functional Enzymes

bioRxiv
Proteins underpin essential biological functions across all kingdoms of life. The capacity to design novel proteins with tailored activities holds transformative potential for biotechnology, medicine, and sustainability. However, since protein functi... read more 

FishWIO: a labeled image dataset of Western Indian Ocean reef fishes for training and testing classification algorithms

bioRxiv
Monitoring fish communities is essential for understanding biodiversity dynamics and coral reef ecosystem health. Underwater imaging provides a non-invasive and repeatable approach for such monitoring, yet analysis of large volumes of video data rema... read more 

Evolutionary profile enhancement improves protein function annotation for remote homologs

bioRxiv
Accurate annotation of protein function is essential for understanding biological processes, yet this remains challenging for proteins lacking characterized homologs or belonging to underrepresented functional classes. Although machine learning appro... read more 

Generative AI designs functional thiolation domains for reprogramming non-ribosomal peptide synthetases

bioRxiv
Large language models and generative protein design promise to accelerate biotechnology, but it remains unclear whether they can engineer dynamic megasynth(et)ases whose activity depends on transient, context-specific domain interfaces. Nonribosomal ... read more 

Cultryx: Precision Diagnostic Stewardship for Blood Cultures Using Machine Learning

medRxiv
Background: The 2024 blood culture bottle shortage brought diagnostic resource allocation to the forefront, reflecting persistent, foundational challenges with low-value testing and empiric treatment approaches under clinical uncertainty. Objective: ... read more 

Pan-cancer tumour classification and risk stratification from whole-genome somatic variants via dual-task representation learning

medRxiv
Tumour typing from whole-genome sequencing is increasingly accurate, yet molecular subtyping from somatic variants remains challenging because of tumour heterogeneity and inconsistent clinical annotations. Here, we present Mutation-Attention Dual-Tas... read more 

A spatial multi-omic portrait of survival outcome for clear cell renal cell carcinoma

medRxiv
Clear cell renal cell carcinoma (ccRCC) is the leading cause of kidney cancer-related death, but how the tumor microenvironment shapes patient survival is not completely understood. Here, we describe the characterization of ccRCC tumor ecosystems fro... read more 

Intelligent Guidance and Diagnostic Assistance for Handheld Ultrasound: Actor-Critic Based Approach for Carotid Artery and Thyroid Examination

medRxiv
Handheld ultrasound devices have revolutionized point-of-care diagnostics, but their effectiveness remains limited by operator dependency and the need for specialized training. This paper presents an intelligent guidance and diagnostic assistance sys... read more