Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 45,071 to 45,080 of 224,055 articles

GEN-KnowRD: Reframing AI for Rare Disease Recognition

medRxiv
Rare diseases affect over 300 million people worldwide, yet patients often endure years-long diagnostic delays that limit timely intervention and trial opportunities. Computational rare disease recognition (RDR) remains constrained by knowledge resou... read more 

Early treatment outcome prediction in metastatic castration-resistant prostate cancer utilizing 3-month tumor growth rate (g-rate) based machine learning model

medRxiv
Summary Background Once the treatment starts, early prediction of treatment benefit and its correlation with overall survival (OS) remains challenging in metastatic castration-resistant prostate cancer (mCRPC). Existing prognostic models require long... read more 

Physics-Based Growth and Remodeling Modeling for Virtual Abdominal Aortic Aneurysm Evolution and Growth Prediction

medRxiv
Computational growth and remodeling (G&R) models have been extentively used to investigate abdominal aortic aneurysm (AAA) progression and to support clinical decision-making. However, the development of robust predictive models is often limited by t... read more 

Multi-Omics Integration of Transcriptomics and Metabolomics with Machine Learning Uncovers Novel Risk Factors for Alzheimer's disease

medRxiv
Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline, memory impairment, and functional deterioration. Its complex pathogenesis involves amyloid plaques, tau tangles, neuroinflammation, and synaptic ... read more 

Multistate Animal-Contact-Related Nontyphoidal Salmonella enterica Outbreaks in the United States, 2009-2022: Network and Machine Learning Analyses of Exposure Sources, Settings, and Serovars

medRxiv
Background: Nontyphoidal Salmonella enterica (NTS) is a major public-health threat in the United States of America (U.S.). Evaluating associations between serovars, exposure sources, and settings in multistate outbreaks can reveal the drivers of NTS ... read more 

NN-Assisted Image Analysis for Quantifying Intracellular Trypanosoma cruzi Infection

bioRxiv
Trypanosoma cruzi infection remains a central, yet methodologically challenging step in Chagas disease research and early-stage drug discovery. Current approaches largely rely on manual microscopy-based counting or on genetically modified parasites, ... read more 

Transcriptomic profiling of mouse mammary tumors enables prognostic and predictive biomarker discovery for human breast cancers

bioRxiv
The development and validation of prognostic and predictive biomarkers in breast cancer is limited by the availability of well-annotated datasets linking tumor molecular features to treatment response and survival outcomes. To address this need, we g... read more 

A foundation AI model enhances electron microscopy image analysis

bioRxiv
Electron microscopy (EM) and advanced volume EM have extensive applications in deciphering cellular ultrastructures for life sciences. However, quality issues of EM images significantly impede the precise analysis and discovery of nanoscale biologica... read more 

Exploration of the screening and regulatory mechanisms of biomarkers related to ac4C modification in laryngeal squamous cell carcinoma patients based on single-cell analysis and machine learning

bioRxiv
Background: N4-acetylcytidine (ac4C) modification plays a critical role in cancer development. Exploring ac4C modification in laryngeal squamous cell carcinoma (LSCC) may help elucidate its pathogenesis. Methods: LSCC-related datasets were obtained f... read more 

Phenotypic Bioactivity Prediction as Open-set Biological Assay Querying

bioRxiv
The traditional drug discovery pipeline is severely bottlenecked by the need to design and execute bespoke biological assays for every new target and compound, which is both time-consuming and prohibitively expensive. While machine learning has accel... read more