OBJECTIVE: To evaluate the clinical value of ultra-low-dose CT (ULDCT) with deep learning image reconstruction (DLIR) in the diagnosis of pulmonary nodules. MATERIALS AND METHODS: This was a prospective study that included 115 patients with suspected... read more
Trichoderma fungi support sustainable agriculture by suppressing plant diseases and improving crop performance. However, emerging pathogenicity of Trichoderma warrants further ecological and genetic characterization. Here we used machine learning to ... read more
Post-translationally modified proteins are crucial autoantigens in autoimmune diseases, with citrullinated proteins being key targets of autoantibodies in rheumatoid arthritis (RA). However, accurate citrullinome profiling and autoantigen identificat... read more
Foundation models in artificial intelligence are revolutionizing healthcare by utilizing large-scale unlabelled data for pretraining. However, their intraoperative applications remain underexplored owing to limited surgical data and the challenges of... read more
Despite the increasing recognition of pyroptosis, particularly that involving GSDME, its precise impact on tumor prognosis and the immune microenvironment remains elusive, necessitating a comprehensive investigation in the context of lung adenocarcin... read more
Several essential physiological systems express voltage-gated potassium channels within the KV7 family (comprising KV7.1-7.5), sometimes also co-assembled with auxiliary subunits in the KCNE family (comprising KCNE1-5). An ongoing challenge to KV7 dr... read more
AI-driven multiscale virtual plant cell modeling represents a paradigm shift in plant systems biology, enabling predictive simulation from molecular mechanisms to tissue functions and accelerating the engineering of climate-resilient crops. AI-driven... read more
Journal of imaging informatics in medicine
Mar 3, 2026
Rapid maxillary expansion (RME) is a common method for maxillary transverse deficiency. While the midpalatal suture density (MPSD) ratio is a critical predictor of skeletal responsiveness to RME, its manual measurement on cone-beam computed tomograph... read more
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