Hydrogels that mimic the extracellular matrix can create a microenvironment with various physicochemical cues, which significantly influence stem cell fate with particular emphasis on their immunoregulatory and pro-regenerative functions. However, el... read more
G protein-coupled receptors (GPCRs) play an ubiquitous role in the transduction of extracellular stimuli into intracellular responses and therefore represent a major target for the development of novel peptide-based therapeutics. In fact, approximate... read more
Inhibition is a core cognitive control function whose competence is distributed across the population, with more extreme impairments in psychiatric conditions such as attention deficit hyperactivity disorder (ADHD). The Stop Signal Task (SST) is a wi... read more
Quantitative assessment of optic nerve health requires metrics beyond axon counts alone. Axon density and glial coverage fraction correlate with clinical measures of visual function, yet no existing automated tool extracts optic nerve cross-sectional... read more
Retinal is a chromophore covalently bound to various photoreceptors. Its photo-induced isomerization triggers a series of structural changes named photocycle, leading to diverse biological functions. Despite tremendous advances in structural biology ... read more
Accurate health information is ineffective if patients cannot understand it. Large Language Model (LLM) health research values veridical precision; however, linguistic accessibility remains an under-examined component of output quality and usability.... read more
Artificial intelligence (AI), particularly large language models (LLMs), is increasingly explored in healthcare, yet its real-world usability and safety in high-risk clinical pharmacy tasks remain uncertain. Vancomycin therapeutic drug monitoring (TD... read more
Sudden cardiac death risk is 2-3-fold higher in athletes than in non-athletes. We classify sports-related cardiac arrhythmias using a novel explainability framework comprising data analysis, model interpretability, post-hoc visualisation, and systema... read more
Rationale, Aims and Objectives: Unwarranted clinical variation (UCV) in patient care often arises from contextual factors and contributes to increased costs, unnecessary treatments, and deviations from evidence-based practice. Detecting UCV is challe... read more
Objective: To evaluate modifiable antepartum and intrapartum factors associated with nulliparous, term, singleton, vertex (NTSV) cesarean delivery and to model risk stratified induction timing strategies that minimize cesarean risk across maternal ri... read more
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