Journal of inherited metabolic disease
Mar 1, 2026
Structural brain alterations have been observed in individuals with phenylketonuria (PKU); however, the potential impact of PKU on brain aging remains unexplored. This study investigated brain age in adults with early-treated classical PKU compared t... read more
BACKGROUND: Colorectal cancer (CRC) is a major cause of morbidity and mortality, with chronic inflammation from inflammatory bowel disease (IBD) representing a well-established risk factor. Clarifying shared molecular mechanisms may facilitate early ... read more
BACKGROUND: A comprehensive preoperative assessment of the patient's physical condition is crucial for predicting the prognosis of patients undergoing radical cholecystectomy for gallbladder cancer (GBC). This study aimed to develop a prognostic mode... read more
Purpose To develop a self-supervised chest CT foundation model and evaluate its performance in lung cancer clinical tasks. Materials and Methods In this retrospective multicenter study, the authors developed the Unified CT-Based Lung Cancer Imaging F... read more
Purpose To evaluate the generalizability of adult-trained models for hepatoblastoma segmentation to pediatric patients and to develop two deep learning (DL) models, M P C T and M p M R I , specifically trained on pediatric contrast-enhanced C... read more
Purpose To evaluate the performance of deep learning models integrating multimodal data for predicting microvascular invasion (MVI) in hepatocellular carcinoma and to investigate the impact of different manual annotation methods on performance. Mater... read more
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