Bone tumors such as osteosarcoma and Ewing sarcoma remain among the most challenging cancers to diagnose and monitor because of their biological heterogeneity and overlapping radiological features. Magnetic resonance imaging (MRI) provides detailed a... read more
Neural networks : the official journal of the International Neural Network Society
Mar 1, 2026
The field of scientific machine learning, which originally utilized multilayer perceptrons (MLPs), is increasingly adopting Kolmogorov-Arnold Networks (KANs) for data encoding. This shift is driven by the limitations of MLPs, including poor interpret... read more
Machine learning (ML)-assisted Raman spectroscopy has become a powerful analytical tool for the classification and identification of analytes; however, technical challenges impacting its detection accuracy have not been investigated. This study explo... read more
Spatial transcriptomics has transformed our ability to study tissue architecture at molecular resolution, yet analyzing these data demands navigating dozens of computational methods across incompatible Python and R ecosystems---forcing researchers to... read more
Understanding how small molecules interact with protein binding pockets is central to structure-based drug discovery. Accurately modelling these interactions requires capturing the 3D geometry and physicochemical complementarity of binding interfaces... read more
Deciphering the spatial organization of macromolecular complexes in their native context is central to structural biology. Particle fusion in single-molecule localization microscopy offers a unique capability for high-resolution structural reconstruc... read more
Legitimacy screening, the process of verifying the identity and purpose of customers ordering synthetic nucleic acids, is a primary safeguard against the misuse of synthetic biology. However, the associated costs discourage the adoption of screening ... read more
The gut microbiome regulates many aspects of human biology, including immunity and inflammatory diseases, yet mechanistic discovery and translation remain constrained by fragmented workflows and manual hypothesis integration. Here, we present Eubiota... read more
Accurate cell type classification is essential for a wide range of biomedical applications, including disease diagnosis, drug discovery, and the study of cellular processes. Holographic imaging flow cytometry (HIFC) provides label-free quantitative p... read more
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