Background: Systematic reviews are important for informing public health policies and program selection; however, they are time- and resource-intensive. Artificial intelligence (AI) offers a solution to reduce these labour-intensive requirements for ... read more
Chemical shift-encoded magnetic resonance imaging using high-resolved 3D Dixon techniques enables the non-invasive and radiation-free assessment of whole-body adipose tissue and ectopic fat distribution. Automatic deep learning-based segmentation of ... read more
Background Prognosis and therapeutic management in Parkinson's disease is a challenging task by its highly heterogeneous disease progression and symptoms presentation, lacking biomarkers to predict individual disease trajectories. Objective To determ... read more
Purpose: To systematically evaluate ocular biometric and systemic laboratory factors associated with cataract in highly myopic eyes and to characterize potential nonlinear associations using an interpretable machine learning approach. Methods: This c... read more
Background: Intrinsic capacity (IC) is a key marker of healthy ageing, which captures an individuals physical and mental capacities, measured across five domains: cognitive, locomotor, psychological, vitality, and sensory. Although genetic factors ar... read more
Objective: To clinically evaluate a digital biomarker, the Finger Fold Index (FFI), derived from the ratio of joint diameter to finger fold surface area in hand photographs, for assessing joint swelling in inflammatory arthritis. Methods: Smartphone ... read more
Objective Quantitative assessment of extent of tissue resection following epilepsy surgery requires accurate delineation of the resection cavity on postoperative MRI. Current methods for resection cavity masking are time-consuming and labour-intensiv... read more
BACKGROUND: High-frequency recurrence (HfR, ≥ 2 recurrences) in non-muscle-invasive bladder cancer (NMIBC) poses a significant clinical burden. Current risk models, such as the European Organization for Research and Treatment of Cancer (EORTC), the E... read more
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