Endothelial dysfunction is an important risk factor for the progression of sepsis. The simplified endothelial activation and stress index (s-EASIX) serves as an indirect measure of endothelial activation, whose dynamic changes have an unclear associa... read more
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Feb 26, 2026
BACKGROUND: Ulcerative colitis (UC) is a chronic inflammatory disease characterized by mucosal immune activation and epithelial barrier breakdown. The pathogenic mechanisms underlying UC remain incompletely understood, and identifying key molecular d... read more
Radiopharmaceuticals are biologically active molecules labeled with radionuclides that have advanced the possibility of the nuclear medicine. They support non-invasive, high-resolution diagnostic imaging of molecular and physiological processes in vi... read more
This study aims to establish a multi-objective spray drying process optimization framework, with andrographolide (ADG) amorphous solid dispersion serving as a model drug. The proposed framework integrates Box-Behnken design (BBD), artificial neural n... read more
OBJECTIVES: This study aimed to develop and compare two YOLOv12-based deep learning models-object detection and pose estimation-for the automatic classification of orthodontically induced external apical root resorption (OIEARR) using panoramic radio... read more
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