Breast cancer, characterized by its aggressive pro-gression and high mortality rates, continues to be among the most common types of cancer. While early detection significantly improves survival outcomes, the current standard diagnostic tool, mammogr... read more
Aristolochic acids (AAs) are established human carcinogens strongly associated with upper tract urothelial carcinoma (UTUC). However, the multi-target oncogenic network beyond their genotoxic mechanism remains incompletely elucidated. This study empl... read more
BACKGROUND: NSCLC remains one of the leading causes of death from cancer worldwide. Although brain metastases are indeed common and also a significant issue in some cases, what actually causes different patients with NSCLC to develop this condition o... read more
INTRODUCTION: Alzheimer's disease (AD) is characterized by significant brain atrophy, detectable via structural MRI. There has been less focus on cortical degeneration in subcortical regional deterioration-particularly during the transition from Mild... read more
Colorectal cancer (CRC) continues to be a substantial cause of cancer-related fatality globally, necessitating improved diagnostic and therapeutic strategies. Exosomes, small extracellular vesicles that facilitate intercellular communication, as key ... read more
In this study, a novel riboflavin-mediated ultraviolet/peracetic acid system (RF/UV/PAA) was developed to enhance the degradation of ranitidine. Under optimal conditions, ranitidine was completely removed within 15 min, leading to a 68.9% mineralizat... read more
The precise identification of cancer driver mutations is essential for precision oncology; however, it remains a significant challenge because of the overwhelming presence of passenger mutations and the complexity of mutational processes. In this stu... read more
Environmental DNA (eDNA) analysis depends critically on high-quality reference databases. However, widely used public repositories (e.g., NCBI) frequently suffer from annotation error, species misidentification, and sequence contamination, leading to... read more
Cochrane evidence synthesis and methods
Feb 26, 2026
OBJECTIVES: Systematic evidence reviews (SERs) produced by the U.S. Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Center (EPC) Program use contextual questions to provide context and background information on the topic. Th... read more
BACKGROUND AND AIMS: Although combination antiretroviral therapy has decreased morbidity and mortality in people living with HIV (PLWH), the prevalence of other sexually transmitted and blood-borne infections (STBBIs) is rising within this population... read more
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