BACKGROUND: While AI-assisted polyp detection has advanced significantly, comprehensive AI-based colonoscopy quality assessment tools remain limited. This study aimed to externally validate an AI-based colonoscopy quality assessment tool (AI-CQ) in J... read more
International journal of computer assisted radiology and surgery
Feb 25, 2026
PURPOSE: Central venous catheterization (CVC) is a critical medical procedure for vascular access, hemodynamic monitoring, and life-saving interventions. Its success remains challenging due to the need for continuous ultrasound-guided visualization o... read more
EZH2 (Enhancer-Homozygous Protein 2), as a key epigenetic regulator, is closely associated with multiple cancers. Consequently, the design of EZH2-targeting inhibitors has become a significant focus in drug development. The application of deep learni... read more
Alzheimer's disease (AD) is a powerful neurodegenerative disease characterized by cholinergic deficiency, where the inhibition of acetylcholinesterase (AChE) remains a clinically validated strategy. In our current work, a virtual screening platform s... read more
Isoform-selective inhibition of class I phosphoinositide 3-kinases (PI3Ks) remains a major challenge in oncology and immune-mediated diseases, where dysregulated PI3K signaling drives tumor progression, therapeutic resistance, and aberrant immune act... read more
Accurate body weight measurement is essential for determining the appropriate dose of contrast agent in contrast-enhanced computed tomography (CT) examinations. However, in emergency medicine, obtaining accurate measurements is often challenging, whi... read more
The design of new antimicrobial materials is a critical challenge in chemistry and materials science, driven by the global threat of multidrug-resistant pathogens. Ionic liquids (ILs) represent a highly versatile class of materials, where their chemi... read more
The fundamental principle that selection acts on a gene's function often assumes implicitly that this function is fixed and intrinsic. However, empirical evidence from pangenomics, synthetic biology, and GWAS consistently demonstrates that organismal... read more
Hydrogel-based bioelectrodes are emerging as next-generation platforms for wearable electronics owing to their skin-like softness, biocompatibility, and mixed ionic-electronic conductivity. However, achieving an optimal balance of mechanical complian... read more
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