BACKGROUND: Whether adolescent major depressive disorder (MDD) with psychotic features has a distinct peripheral metabolite signature remains uncertain. We compared targeted plasma neurotransmitter-related metabolites in psychotic MDD, non-psychotic ... read more
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Feb 25, 2026
BACKGROUND AND PURPOSE: Cardiovascular disease (CVD) is the leading cause of death globally [1] as well as the leading cause of death among cancer survivors [2]. The outcomes of CVD mortality among cancer patients, particularly those with breast canc... read more
This article presents a Delphi consensus developed by a panel of editors-in-chief of anaesthesiology and pain medicine journals to guide the responsible use of large language models (LLMs) in academic publishing. LLMs offer potential benefits for sci... read more
Metabolism modulation has emerged as a promising frontier in precision oncology. Nonetheless, the primary gap is the inability to precisely target the unique metabolic vulnerabilities of different cell types in vivo, which has limited clinical transl... read more
Dental materials : official publication of the Academy of Dental Materials
Feb 25, 2026
OBJECTIVE: To develop a machine learning framework using Gaussian Process Regression (GPR) and Bayesian Optimization (BO) to predict and optimize the viscosity of resin composites at two shear rates (0.0106 and 74.4 s-1). METHODS: Fifty-four experime... read more
Journal of the Formosan Medical Association = Taiwan yi zhi
Feb 25, 2026
OBJECTIVE: Machine learning (ML) has advanced predictive modeling in medical diagnosis and risk assessment through large clinical datasets, yet applications for predicting post-cancer depression and anxiety remain limited. This cross-institutional, l... read more
This study introduces a series of machine-learning models based on DeepFrag, our previously published tool designed to guide small-molecule lead optimization through fragment addition. We demonstrate enhanced accuracy by training new DeepFrag models ... read more
Magnetic resonance imaging (MRI) is essential in medical diagnostics, but its resolution is often limited by factors such as scan time, signal-to-noise ratio, and hardware constraints. With the development of deep learning, multi-contrast super-resol... read more
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