Reproductive sciences (Thousand Oaks, Calif.)
Feb 20, 2026
Endometriosis (EMs) is a common chronic inflammatory gynecological disorder. But the exact pathogenetic mechanism of the disease is not clear, with some theories proposing that the disease is caused by the interaction of endocrine, immune, and geneti... read more
OBJECTIVE: To investigate the ability of artificial intelligence-enabled electrocardiogram (AI-ECG) atrial fibrillation (AF) prediction model output and delta age, defined as AI-estimated age minus chronological age, to predict adverse vascular outco... read more
OBJECT: To develop and evaluate a multi-stage computer-aided determination (CAD) method for automated antral follicle count (AFC) and dominant follicle identification using pelvic magnetic resonance imaging (MRI), aiming to overcome the limitations o... read more
BACKGROUND: Angiography is the gold standard for assessing the relationship between cerebral arteries and intracranial tumors, but its use is limited in low- and middle-income countries for various reasons. Contrast-enhanced T1-weighted MRI (T1C) is ... read more
Proteolysis-targeting chimeras (PROTACs) are heterobifunctional molecules composed of an E3 ligase ligand, a linker, and a warhead targeting a protein of interest. Despite their modular structure, accurately identifying and annotating these component... read more
Patients with Hashimoto's thyroiditis (HT) frequently present with concurrent nodular lesions such as nodular goiter and thyroid cancer (especially papillary thyroid carcinoma, PTC), and their risk of PTC is significantly higher than that of non-HT i... read more
Journal of chemical information and modeling
Feb 20, 2026
Drug-like molecules often interact with multiple biological targets. Assessing this polypharmacology is essential for drug development. Here, we trained deep neural networks to associate bioactive molecules up to 80 non-hydrogen atoms reported in ChE... read more
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