BACKGROUND AND PURPOSE: Infections are the leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL) and occur during and after treatment. When deciding on the type of CLL treatment, the risk of infections is typica... read more
Arthritis & rheumatology (Hoboken, N.J.)
Feb 19, 2026
OBJECTIVE: This study investigated that serum metabolomics, prior to ULT initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat-to-target ULT. METHODS: We studied a multicenter prosp... read more
Journal of chemical information and modeling
Feb 19, 2026
Peptide therapeutics are rapidly advancing in the biopharmaceutical field, but the high cost and low throughput of experimental screening call for more efficient discovery pipelines. We present an AI-driven framework for exhaustive hexapeptide screen... read more
Endometriosis occurs when endometrial tissue grows outside the uterus, affecting millions of women worldwide. Despite extensive research, its cellular mechanisms remain unclear, complicating both diagnosis and treatment. This study presents the devel... read more
PURPOSE: To explore the role of MRI-based habitat radiomics in assessing the metastatic status of renal cell carcinoma (RCC). METHODS: This study retrospectively collected 241 patients with RCC who underwent nephrectomy and lymphadenectomy at four ce... read more
Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) represents a high-risk subtype of AML, characterized by poor prognosis and limited therapeutic options. Recent updates in the WHO and ICC classifications have redefined AML-MRC, emp... read more
UNLABELLED: This study aimed to identify patient groups in which myeloablative conditioning (MAC) or reduced-intensity conditioning (RIC) regimens induced superior progression-free survival (PFS) in patients with acute myeloid leukemia (AML) in compl... read more
Environmental monitoring and assessment
Feb 19, 2026
Urban flooding is increasingly exacerbated by the accumulation of floating debris in rivers, which obstructs water flow, degrades water quality, and poses significant risks to human safety and environmental sustainability. Effective monitoring of flo... read more
Patients presenting to neurology clinics commonly have a complex history of comorbidities and partially documented health trajectories, making it essential to reliably extract comorbidity information from historical records. However, existing extract... read more
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