AI Medical Compendium

Uncovering the silent invaders: Dormant tumour cells in the brain microenvironment.

Critical reviews in oncology/hematology Feb 18, 2026

Brain metastasis remains a lethal clinical challenge, largely driven by dormant tumour cells (DTCs). This reversible quiescent state enables disseminated cancer cells to evade conventional therapies and eventually cause relapse. This review provides ... read more

OPU-NET-DADENA: Optimized deep learning ensemble with u-net segmentation for early detection of diabetic retinopathy.

Microvascular research Feb 18, 2026

One of the most significant microvascular complications of diabetes mellitus (DM) is diabetic retinopathy (DR). In the early stages, patients with DR may not exhibit any noticeable symptoms. It is a diabetic disorder that damages retinal blood vessel... read more

Integrating machine learning and molecular simulations for the design of potent HDAC2 inhibitors in diffuse large B-cell lymphoma.

Computational biology and chemistry Feb 18, 2026

Histone deacetylase 2 (HDAC2) plays a critical role in the pathogenesis of diffuse large B-cell lymphoma (DLBCL), positioning it as an attractive therapeutic target. In this study, we applied an integrated computational strategy that combined machine... read more

Self-supervised ultrasound B-mode strain elastography using SMURF.

Ultrasonics Feb 18, 2026

Displacement tracking is an integral part of ultrasound strain elastography (USE) and various approaches have been proposed over the last three decades. However, limitations exist in the estimation of the lateral displacement field for several of the... read more

Multiplexed biosensing: A review of surface plasmon resonance platforms for biomarker analysis.

Talanta Feb 18, 2026

Surface plasmon resonance (SPR) has emerged as an important optical technology for the real-time, label-free analysis of biomolecular interactions. While its utility in detecting single analytes is well-established, the growing complexity of disease ... read more

Deep Learning-Based Multi-Stage System for Automated Tooth Detection and Segmentation in Orthodontic Photography.

Journal of imaging informatics in medicine Feb 18, 2026

This study aimed to develop and evaluate a fully automated, artificial intelligence-driven system for tooth detection and segmentation from complete orthodontic photographic plates, with the goal of improving clinical outcomes and workflow efficiency... read more

Neuropathologic basis of quantitative susceptibility mapping in the substantia nigra: contributions of tau, pigmented neurons, and iron.

Acta neuropathologica Feb 18, 2026

Quantitative susceptibility mapping (QSM) on MRI quantifies tissue magnetic susceptibility, which increases with iron accumulation, myelin loss, and neuroinflammation. Elevated QSM in the substantia nigra (SN) has been reported in Lewy body disease a... read more

Extending the range of graph neural networks with global encodings.

Nature communications Feb 18, 2026

Graph Neural Networks (GNNs) are routinely used in molecular physics, social sciences, and economics to model many-body interactions in graph-like systems. However, GNNs are inherently local and can suffer from information flow bottlenecks. This is p... read more

SwarmMAP: swarm learning for decentralized cell type annotation in single cell sequencing data.

NPJ systems biology and applications Feb 18, 2026

Rapid technological progress now enables large-scale generation of single-cell data. Many laboratories can produce single-cell transcriptomic profiles from diverse tissues. A key step in single-cell analysis is unsupervised clustering followed by cel... read more

Geochemical fingerprinting and machine learning for authenticating sparkling wine origins.

NPJ science of food Feb 18, 2026

The global wine market faces persistent threats from counterfeiting, particularly for high-value segments like sparkling wines. Traditional authentication methods relying on supply chain traceability and geographical indications are insufficient to c... read more

Artificial Intelligence Medical Compendium