Societies are aging rapidly in parallel with the increasingly earlier onset of serious diseases in younger populations. These and other factors are creating a substantial disparity between healthspan, the period of life where an individual is free fr... read more
Heart failure with preserved ejection fraction (HFpEF) is an increasingly common cause of morbidity and mortality in older adults that is driven by cardiac and non-cardiac mechanisms. Physical rehabilitation improves frailty and functional capacity i... read more
Large language models (LLMs) are increasingly used for qualitative analysis in substance use research, yet their performance relative to human coders remains underexplored. This study compares ChatGPT-4.0 with human coders in identifying and describi... read more
Cross-jurisdictional pharmaceutical compliance requires comparative analysis of regulatory requirements across jurisdictions such as the US FDA and Chinas NMPA. Although large language models (LLMs) are increasingly explored for healthcare-related ap... read more
Osteoporosis is a silent yet debilitating disease that often remains undetected until fractures occur. While early prediction is crucial, most studies combine male and female datasets to train a single model, introducing bias since osteoporosis risk ... read more
Background: Large language models (LLMs) show promise for clinical decision support, yet most validation studies evaluate single models, leaving questions about generalizability and vendor dependence unanswered. We assessed whether a standardized bio... read more
Background: Australian health practitioners are regulated under the Health Practitioner Regulation National Law, with serious conduct matters referred to state and territory tribunals. Despite thousands of published tribunal decisions, no prior study... read more
Type 1 narcolepsy (NT1), a disorder caused by the loss of hypocretin/orexin transmission, is characterized by daytime sleepiness and symptoms where Rapid Eye Movement (REM) sleep, a state normally occurring from middle to late in the night, can inter... read more
Background: The growing interest in applying artificial intelligence in personalized nutrition is challenged by the complex nature of dietary advice that must balance health, economic, and personal factors. Though automated solutions using either Lin... read more
Background and Aims: Choledocholithiasis (CDL) is a common condition that can lead to serious complications, requiring effective risk stratification for timely intervention. While current guidelines use clinical predictors, imaging, and laboratory ma... read more
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