Microscopy images are frequently downsampled due to acquisition and computational constraints, requiring reconstruction before downstream analysis. While super-resolution (SR) is typically assessed using pixel-level fidelity metrics, its impact on de... read more
Cryogenic electron microscopy (cryo EM) has become a widely used technique for determining the three-dimensional structures of biological macromolecules. Despite its advantages, building accurate structural models from cryo EM data remains challengin... read more
Living materials derive function from tightly coupled cellular and material processes to deliver adaptive and therapeutic capabilities, yet their predictive design remains constrained by fragmented, cross-disciplinary knowledge and experience-driven ... read more
Language relies on a hierarchy of sensory and cognitive processes, yet how different levels of this hierarchy are supported by distinct neural architectures remains unclear. Here we show that semantic processing, compared with phonological processing... read more
Accurate monitoring of microalgae is essential for assessing marine ecological health and preventing harmful algal blooms in ocean engineering. Current in situ identification methods often suffer from limited discriminative feature extraction and ina... read more
Assessing the human infection potential of emerging coronaviruses remains a critical challenge for global health preparedness. In this study, we developed a machine learning-based framework to predict the human infection potential of coronaviruses an... read more
We present a deep learning model that predicts left atrial (LA) volume from standard 12-lead ECG recordings and basic patient data. This approach offers a low-cost, scalable alternative to MRI-based LA volume measurement, which remains the clinical g... read more
Magnetic Resonance Spectroscopy Imaging (MRSI) offers spatially-resolved, neurometabolic information, acquired non-invasively at whole-brain scales from human subjects. Analysis of MRSI however, is extremely challenging. The metabolic information is ... read more
Background: Large language models show promise for clinical decision support, yet their propensity for hallucination--generating plausible but unsupported claims--poses substantial patient safety risks. Retrieval-augmented generation (RAG) is widely ... read more
Background: Pancreatic ductal adenocarcinoma is one of the most aggressive and lethal malignancies of the gastrointestinal tract. The poor prognosis is largely attributed to late-stage diagnosis, pronounced tumor heterogeneity, and limited therapeuti... read more
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