The purpose of this study was to evaluate the predictive value of monocyte-to-lymphocyte ratio (MLR) on the short-term (28 days) and long-term (365 days) mortality risk in patients with acute pancreatitis (AP) using multiple statistical and machine l... read more
MOTIVATION: Flow cytometry (FC) is a widely used technique for analysing cells or particles based on the fluorescence of specific markers. Thresholds for fluorescence are typically set manually, a laborious, subjective process that scales poorly as F... read more
Spatially resolved transcriptomics (SRT) and spatially resolved proteomics (SRP) data enable the study of gene expression and protein abundances within their precise spatial and cellular contexts in tissues. Certain SRT and SRP technologies also capt... read more
MOTIVATION: Predicting immunoglobulin-antigen (Ig-Ag) binding remains a significant challenge due to the paucity of experimentally-resolved complexes and the limited accuracy of de novo Ig structure prediction. RESULTS: We introduce IgPose, a general... read more
Artificial intelligence (AI) models for diagnostic imaging face reproducibility challenges due to inconsistent reporting. Existing guidelines also lack specificity for imaging-based AI diagnostics, particularly regarding clinical usability and techni... read more
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