BACKGROUND: Plasma biomarkers have emerged as robust indicators of Alzheimer's disease (AD) pathology, offering accessible tools for staging and stratification. However, their expression across globally diverse populations remains poorly characterize... read more
BACKGROUND: Epigenetic modifications play a vital role in the pathogenesis of human diseases, particularly neurodegenerative disorders such as Alzheimer's disease, where dysregulated histone modifications are strongly implicated in disease mechanisms... read more
The journals of gerontology. Series A, Biological sciences and medical sciences
Feb 14, 2026
BACKGROUND: Research suggests aging is a coordinated physiological decline occurring in multiple systems and at multiple biological levels. However, it is largely unknown how general biological aging and specific systemic aging co-occur and influence... read more
Medical professionals rely on MRI scans to evaluate brain tumors, a task prone to fatigue and subjective interpretation. This study enhances the YOLOv10 model by integrating two innovative modules: AvConv module and Bidirectional Pathway, both design... read more
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Feb 14, 2026
PURPOSE: Endoscopic endonasal and transcranial approaches are used for the resection of various pathological lesions in neurosurgery, especially pituitary adenomas, craniopharyngiomas, chordomas, or meningiomas. The video feed provided by endoscopes ... read more
The pervasive expectations about ideal body types in Western society can lead to body image concerns, dissatisfaction, and in extreme cases, eating disorders and other psychopathologies related to body image. While previous research has focused on on... read more
PURPOSE: Non-small cell lung carcinoma (NSCLC) is a leading cause of cancer-related mortality worldwide, highlighting the urgent need for early detection and targeted therapies. While lipopolysaccharide (LPS) metabolism and circadian rhythm disruptio... read more
The International journal on drug policy
Feb 14, 2026
BACKGROUND: British Columbia (BC), Canada, continues to experience persistently high rates of unregulated drug toxicity. While the presence of fentanyl in the drug supply is well-established, less is known about how fluctuations in its concentration ... read more
Marine microplastic pollution presents a critical environmental challenge, affecting ecosystems, wildlife, and human health as millions of tons of plastic waste enter oceans each year. Microplastics, due to their small size, are difficult to detect a... read more
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