The Journal of investigative dermatology
Feb 13, 2026
Recent advances in artificial intelligence (AI) and multimodal data collection are revolutionizing dermatology. Generative AI and machine-learning approaches offer opportunities to enhance the diagnosis and treatment of autoimmune and inflammatory sk... read more
The scPrediXcan framework enables cell-type-specific transcriptome-wide association studies (TWASs) by integrating deep learning-based prediction of gene expression from DNA sequence and epigenetic features. We present a protocol for scPrediXcan: tra... read more
Minor salivary gland biopsy occupies a distinctive position in the evaluation of Sjögren disease (SjD), offering diagnostic and prognostic insights that are rarely achievable in other systemic autoimmune conditions. It contributes essential diagnosti... read more
Journal of medical imaging and radiation sciences
Feb 13, 2026
INTRODUCTION/BACKGROUND: Segmentation of gastrointestinal (GI) organs-at-risk (OARs) is a critical yet time-consuming step in MR-guided adaptive radiotherapy (MRgRT), with manual delineation prone to inter- and intra-observer variability. While deep ... read more
Ecotoxicology and environmental safety
Feb 13, 2026
High-quality prediction of ozone concentrations is essential for formulating effective environmental policies. The integration of monitoring data of volatile organic compounds (VOCs), key precursors in ozone formation, through dimensionality reductio... read more
Current opinion in genetics & development
Feb 13, 2026
The genetic architecture of psychiatric disorders is highly complex, with genome-wide association studies implicating thousands of risk loci. A central challenge is that most of these variants are located in noncoding regions, making it difficult to ... read more
BACKGROUND: Pulmonary embolism (PE) is a leading cause of preventable death, yet statistical prediction models have shown inconsistent validity. Our primary objective was to determine if a machine learning model trained with data routinely collected ... read more
With the rapid advancement of protein structure prediction techniques and the explosive growth of predicted structural data, existing estimation of model accuracy (EMA) methods struggle to balance computational efficiency with estimation performance.... read more
Liquid biopsy has revolutionized noninvasive disease diagnosis and monitoring by detecting circulating biomarkers such as tumor-derived DNA, miRNAs, proteins, exosomes, and circulating tumor cells in body fluids. Conventional single-analyte approache... read more
RATIONALE AND OBJECTIVES: Rapid advancements in multimodal large language models (LLMs) highlight their expanding potential in radiology education and assessment. This study aims to evaluate and compare the performance of three state-of-the-art LLMs;... read more
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