AI Medical Compendium

Brain Mechanisms of Pain Anticipation in Chronic Low Back Pain: Insights into Phenotypical Responses to Mind-Body Therapy.

The journal of pain Feb 12, 2026

Pain perception and emotional processing share common predictive mechanisms influenced by anticipation, expectation, and uncertainty. This study identifies distinct neural phenotypes of pain anticipation in chronic low back pain(cLBP) and examines th... read more

Thalamocortical and corticostriatal pathways in the progression from acute to chronic musculoskeletal pain: an fMRI study.

The journal of pain Feb 12, 2026

Most people experience acute pain as a temporary condition, while a small subset develops chronic pain. The role of pain-related circuits driving this transition remains unclear. Using UK Biobank data and an independent dataset (OpenPain), we analyze... read more

Integrated bioinformatics and machine learning approaches reveal that Venenum bufonis acts against acute pharyngitis by inhibiting the p38 MAPK/ERK-MKNK1-eIF4E signaling pathway.

Journal of ethnopharmacology Feb 12, 2026

ETHNOPHARMACOLOGICAL RELEVANCE: Venenum bufonis (VB) has been used for centuries in Asia to treat pharyngitis. However, its active components and mechanisms require further elucidation. AIMS OF THE STUDY: This study aimed to identify the active compo... read more

Therapeutic potential of pharmacological components of Salvia miltiorrhiza against atherosclerosis: A preclinical systematic review and meta-analysis.

Journal of ethnopharmacology Feb 12, 2026

ETHNOPHARMACOLOGICAL RELEVANCE: Atherosclerosis (AS) severely threatens global health, while current therapies exhibit limitations. Recognized as a 'superior-grade' herb in the Shennong Ben Cao Jing, Salvia miltiorrhiza Bunge (Danshen) has been shown... read more

Neuroimaging-derived brain age as a new promising biomarker in mental disorders.

Neuroscience and biobehavioral reviews Feb 12, 2026

Mental disorders are frequently associated with accelerated brain aging, yet the diagnostic and classificatory utility of brain age remains uncertain. This study aimed to evaluate the diagnostic value of brain age across multiple mental disorders and... read more

An integrative genomic framework to identify remote ischemic preconditioning-responsive genes associated with stroke risk.

Experimental neurology Feb 12, 2026

BACKGROUND: Remote ischemic preconditioning (RIPC) is a promising, non-invasive strategy for reduction in ischemic injury after stroke, yet its molecular mechanisms and translatability from animal models to humans remain insufficiently defined. In pa... read more

Street-level ambient fine particulate matter and tuberculosis: A machine learning and Bayesian spatiotemporal analysis.

Environmental pollution (Barking, Essex : 1987) Feb 12, 2026

Tuberculosis (TB) remains a leading cause of death from infectious diseases globally, yet evidence linking short-term ambient fine particulate matter (PM2.5) exposure to TB incidence at fine spatial scales is limited. We investigated the street-level... read more

Crucial Conversations: Psychiatric Diagnosis and Shared Decision-Making With Adolescents in the Age of Social Media and Artificial Intelligence.

Journal of the American Academy of Child and Adolescent Psychiatry Feb 12, 2026

The role of using ChatGPT AI in writing medical scientific articles - Two years after.

Journal of stomatology, oral and maxillofacial surgery Feb 12, 2026

Two years after the first evaluation of ChatGPT (GPT-3.5) for medical scientific writing, this short communication reassesses its capabilities using the GPT-5 model. Under the same experimental protocol as in 2023, GPT-5 generated a coherent and fact... read more

Spatiotemporal Remodeling of Bone as a Reversibly Adaptive Biological Material in Djungarian Hamsters under Regulated Photoperiod Conditions.

Acta biomaterialia Feb 12, 2026

Bone loss in humans is typically progressive and difficult to reverse, posing challenges for both pharmacological therapy and the long-term performance of bone replacement materials. Photoperiod-sensitive species such as the Djungarian hamster underg... read more

Artificial Intelligence Medical Compendium