Journal of chemical information and modeling
Feb 12, 2026
Protein-small-molecule interactions are fundamental to cellular regulation and represent critical targets for therapeutic intervention. Accurate identification of binding residues is essential for elucidating molecular recognition mechanisms and guid... read more
Foundation models (FMs) are large deep learning models pre-trained on vast heterogeneous datasets through self-supervised learning that are adaptable to diverse downstream tasks with minimal fine-tuning. In pediatric radiology, where data scarcity, r... read more
Sudden cardiac death (SCD) remains one of the leading causes of death despite major advances in cardiovascular diagnostics and treatment. Evidence supporting primary prophylactic implantable cardioverter defibrillator (ICD) implantation is still deri... read more
OBJECTIVES: Large language models (LLMs) like generative pre-trained transformer (GPT) can simplify radiology reports for medical laypersons, but privacy concerns limit their clinical applicability. This study compares closed-weight and in-hospital d... read more
Clinical cancer research : an official journal of the American Association for Cancer Research
Feb 12, 2026
PURPOSE: Immune checkpoint blockade (ICB) benefits only a subset of sarcoma patients. Biomarkers of response and resistance are needed to help guide patient selection. PATIENTS AND METHODS: We analyzed peripheral blood and tumor samples from sarcoma ... read more
To synthesize and critically appraise applications of machine learning (ML) in pediatric cardiac intensive care, focusing on algorithm performance, validation rigor, and readiness for clinical decision-support integration. Scoping review of studies a... read more
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Feb 12, 2026
PURPOSE: Cancer survivors often experience long-term consequences affecting their Health-Related Quality of Life (HRQoL). Sociodemographic factors, clinical characteristics, and health-related behaviours influence HRQoL, making some individuals vulne... read more
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