OBJECTIVES: To describe the structured process of threshold optimisation for a commercially available multiclass chest X-ray (CXR) deep learning model, to evaluate its diagnostic performance across different operating thresholds, and to estimate its ... read more
Fluorescence-guided surgery (FgS) is increasingly used across oncologic specialties to enhance intraoperative visualisation of tumour tissue and lymphatic drainage; however, its clinical impact remains limited by heterogeneous tracer uptake, variable... read more
BACKGROUND: Neuroimmune, circadian, autonomic, and gut-brain processes jointly shape vulnerability to postoperative delirium and long-term cognitive decline, yet their integrated contribution remains unclear. METHODS: In this prospective cohort (n = ... read more
Electrocatalytic NO reduction reaction (NORR) enables the conversion of hazardous NO gases into valuable NH₃ under ambient conditions. However, due to the slow reaction kinetics and low Faraday efficiency of NORR, it is essential to explore active an... read more
Drug discovery is a complex and systematic process aimed at finding new treatment methods that can prevent or treat specific diseases. Accurately predicting the interaction and binding affinity between drugs and targets is one of the key steps in mod... read more
International journal of biological macromolecules
Feb 12, 2026
Age-related osteoporosis is increasingly recognized as a disease of stem cell dysfunction, hallmarked by the skewed lineage commitment of mesenchymal stem cells (MSCs) away from osteogenesis towards adipogenesis. This functional decline is closely li... read more
Photodiagnosis and photodynamic therapy
Feb 12, 2026
BACKGROUND: This study aimed to assess the value of blood plasma autofluorescence spectroscopy in classifying renal injury after renal transplantation. METHODS: The researchers included 86 patients after kidney transplantation and established five cl... read more
European heart journal. Digital health
Feb 12, 2026
AIMS: The role of electrocardiography (ECG) has been limited in the preoperative risk evaluation in noncardiac surgery due to its low prognostic value. We aimed to evaluate the utility of an AI-enabled ECG (QCG-Critical score) in predicting 30-day po... read more
This study explores the linguistic differences between AI-generated content and human-written texts, particularly in Portuguese. We created two datasets: one with factual and false human-written texts, and another with texts generated by advanced, la... read more
International journal of cardiology. Cardiovascular risk and prevention
Feb 12, 2026
BACKGROUND: Efficient community-based screening for individuals at high risk of mortality is a major public health challenge. While many predictors have been proposed, there is limited consensus on which factors are both robust and practical for popu... read more
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