Bacterial infections are a major cause of morbidity and mortality among children under five in low- and middle-income countries (LMICs). Children in LMICs are exposed to and colonized by a range of pathogenic bacteria, yet patterns of bacterial excha... read more
Loneliness and psychological well-being are increasingly recognized as critical public health concerns, yet their multi-factorial determinants remain poorly understood. Traditional research often examines demographic, lifestyle, or social variables i... read more
Objective: Post-thrombotic syndrome (PTS), a common complication of deep vein thrombosis, lacks objective diagnostic biomarkers and its molecular mechanisms remain poorly understood. This study aimed to identify plasma biomarkers and clarify pathways... read more
INTRODUCTION: Cognitively unimpaired (CU) adults show substantial variation in their risk of developing mild cognitive impairment (MCI), yet most subtyping approaches emphasize neurobiological or cognitive features rather than modifiable risk factors... read more
Wastewater-based epidemiology provides a low-cost, scalable view of community infection dynamics, but converting these signals into actionable epidemiological insights remains difficult. Mechanistic models offer interpretability, yet, assumptions suc... read more
Objective: Adverse events (AEs) resulting from medical interventions are significant contributors to patient morbidity, mortality, and healthcare costs. Prediction of these events using electronic health records (EHRs) can facilitate timely clinical ... read more
Background: Natural language processing (NLP) systems integrated into clinical workflows show promise for detecting early cognitive impairment, yet causal evidence from real-world implementation remains limited. Observational studies comparing outcom... read more
Background: Inadequate data in electronic health records can create problems for clinical decision support systems and predictive modelling tools. ICU patients with heart failure may have incomplete physiological data as a result of irregular patient... read more
While Large Language Models (LLMs) have shown promise in clinical decision support, current Retrieval-Augmented Generation (RAG) paradigms face a fundamental bottleneck in rare disease diagnosis: the scarcity, privacy restrictions, and extreme hetero... read more
Histopathologic evaluation remains central to cancer diagnosis and treatment planning, yet the molecular programs underlying distinct tissue morphologies are not routinely accessible in clinical workflows. Spatial transcriptomic/proteomic platforms p... read more
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