AI Medical Compendium

Integration of Multi-Omics and Machine Learning Identifies TGFB1 and SERPINE1 as Biomarkers of Vascular Smooth Muscle Cell Senescence in Intracranial Aneurysms.

Translational stroke research Feb 10, 2026

Intracranial aneurysms (IAs) are severe cerebrovascular disorders lacking effective gene therapy or pharmacological interventions. Vascular smooth muscle cell (VSMC) senescence has been associated with various cardiovascular and cerebrovascular disea... read more

Machine learning, whole-transcriptome and integrative omics analysis reveals key regulatory networks governing human spermatogonial stem cells.

Clinical and experimental medicine Feb 10, 2026

Clinical feasibility test of 60 kVp double-low-dose coronary CT angiography with a deep learning reconstruction algorithm.

Insights into imaging Feb 10, 2026

OBJECTIVES: To test the feasibility of 60 kVp double-low-dose coronary CT angiography (CCTA) with a deep learning reconstruction (DLR) algorithm. MATERIALS AND METHODS: Eighty-nine patients (44 females, 59.9 ± 13.2 years, 23.1 ± 3.3 kg/m2) with known... read more

Development and validation of a prognosis model for low-grade gliomas based on metabolic gene risk scoring and immune microenvironment interaction.

Discover oncology Feb 10, 2026

PURPOSE: Low-grade gliomas(LGGs) show significant clinical and molecular heterogeneity, complicating progression prediction with conventional indicators. Metabolic reprogramming, a cancer hallmark, is linked to immune microenvironment remodeling, yet... read more

Identification and validation of the protective gene BCAT2 related to amino acid metabolism in idiopathic pulmonary fibrosis.

Clinical and experimental medicine Feb 10, 2026

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease, with unknown pathogenesis and no effective treatment. Identifying the key molecular of IPF in underlying mechanisms is critical for developing targeted therapies. Differenti... read more

Correction: Resilient back-propagation machine learning-based classification on fundus images for retinal microaneurysm detection.

International ophthalmology Feb 10, 2026

Combining Spatial Transcriptomics and Machine Learning Unravels Fibroblast-Related Biomarkers in Ulcerative Colitis.

Inflammation Feb 10, 2026

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent mucosal inflammation. While fibroblasts contribute to tissue repair and fibrosis, their role in UC pathogenesis remains incompletely understood. Single-cell R... read more

Artificial intelligence-derived transition zone PSA density as a triage tool to reduce unnecessary prostate systematic biopsies in MRI-negative men.

Insights into imaging Feb 10, 2026

OBJECTIVES: The study aimed to assess the predictive performance of transition zone PSA density (TZ-PSAD) compared to conventional PSA density (PSAD) in detecting clinically significant prostate cancer (csPCa) among patients with negative pre-biopsy ... read more

Improved schizophrenia detection using structural MRI with multi-scale transform and deep orthogonal features.

Physical and engineering sciences in medicine Feb 10, 2026

Smartphone-Based Portable Slit Lamp in Anterior Segment Diseases: A Narrative Review of Clinical Assessment and Integration with Artificial Intelligence.

Ophthalmology and therapy Feb 10, 2026

Smartphone-based portable slit lamps are rapidly evolving from simple add-ons into practical, low-cost front-line tools for anterior segment care beyond traditional clinical settings. By integrating high-performance smartphone cameras with compact op... read more

Artificial Intelligence Medical Compendium