Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease, with unknown pathogenesis and no effective treatment. Identifying the key molecular of IPF in underlying mechanisms is critical for developing targeted therapies. Differenti... read more
PURPOSE: Low-grade gliomas(LGGs) show significant clinical and molecular heterogeneity, complicating progression prediction with conventional indicators. Metabolic reprogramming, a cancer hallmark, is linked to immune microenvironment remodeling, yet... read more
OBJECTIVES: To test the feasibility of 60 kVp double-low-dose coronary CT angiography (CCTA) with a deep learning reconstruction (DLR) algorithm. MATERIALS AND METHODS: Eighty-nine patients (44 females, 59.9 ± 13.2 years, 23.1 ± 3.3 kg/m2) with known... read more
Intracranial aneurysms (IAs) are severe cerebrovascular disorders lacking effective gene therapy or pharmacological interventions. Vascular smooth muscle cell (VSMC) senescence has been associated with various cardiovascular and cerebrovascular disea... read more
Multimodal profiling of inflammatory bowel disease (IBD) patient tissue and blood samples has revealed the disease spectrum in unprecedented detail, and cellular and molecular correlates of disease severity and outcome in IBD have been elaborated. In... read more
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