Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 52,741 to 52,750 of 225,341 articles

Unified imputation of missing data modalities and features in multi-omic data via shared representation learning

bioRxiv Feb 6, 2026
Multi-omic studies promise a more comprehensive view of biological systems by jointly measuring multiple molecular layers. In practice, however, such datasets are rarely complete: entire molecular modalities may be missing for many samples, and obser... read more 
bioinformatics

BOLE: A Knowledge-Enhanced Multi-Agent Framework for Intelligent Genomic Breeding

bioRxiv Feb 6, 2026
Genomic breeding has become increasingly data-intensive, yet the practical integration of heterogeneous bioinformatics tools into coherent analytical workflows remains a major bottleneck. To address this, we present BOLE, a knowledge-enhanced multi-a... read more 
genomics

Depth-Sensitive Optical Property Characterization Using Multi-Frequency Laparoscopic SFDI

bioRxiv Feb 6, 2026
Accurate knowledge of tissue absorption () and reduced scattering (s'), parameters is required to plan and monitor laparoscopic chemophototherapy (CPT) in ovarian cancer, including light dosimetry and quantitative fluorescence mapping of porphyrin ph... read more 
bioengineering

Adaptive spatio-temporal phase retrieval for ultra-short pulse wavefront shaping

bioRxiv Feb 6, 2026
Beam shaping of ultra-short pulses is essential for medical ultrasound, where single-cycle excitations are required to achieve high axial resolution and improve frame rate. Conventional methods, such as the Gerchberg Saxton (GS) algorithm or more rec... read more 
bioengineering

Practical utility of sequence-to-omics models for improving the reproducibility of genetic fine-mapping

bioRxiv Feb 6, 2026
Recent advances in deep learning have led to the development of sequence-to-omics (S2O) models that predict molecular phenotypes directly from DNA sequences. Here, we systematically evaluate the utility of these models, e.g., AlphaGenome, Borzoi, Enf... read more 
genetics

A lightweight, ultrafast and general embedding framework for large-scale spatial omics data

bioRxiv Feb 6, 2026
Deciphering ultra-large-scale omics data with minimal resources while maintaining high computational efficiency is a longstanding challenge in biology. Here, we present Local Pooling (LP), a lightweight, ultrafast and general framework that leverage ... read more 
bioinformatics

Macro-Equi-Diff (MED): Scaffold-based Macrocycles Generation Using Equivariant Diffusion

bioRxiv Feb 6, 2026
Macrocyclic compounds are essential in drug discovery as they can modulate protein-protein interactions and enhance selectivity. Their structural complexity enables access to molecular diversity beyond traditional small molecules; however, designing ... read more 
bioinformatics

Delphi: Deep Learning for Polygenic Risk Prediction

medRxiv Feb 6, 2026
Polygenic scores (PGS) are relative measures of an individual's genetic propensity to a particular trait or disease. Most PGS methods use a regression framework for polygenic modeling and assume that mutation effect estimates are constant across indi... read more 
genetic and genomic medicine

Maximizing impact of explainable artificial intelligence in radiotherapy: a critical review.

Physics in medicine and biology Feb 6, 2026
Objective.Artificial intelligence (AI) can enable automation, improve treatment accuracy, allow for a more efficient workflow, and improve the cost-effectiveness of radiotherapy (RT). To implement AI in RT, clinicians have expressed a desire to under... read more 

Screening for Tumor Microtube-Targeting Drugs Identifies PKC Modulators as Multipotent Inhibitors of Glioblastoma Progression.

Cancer discovery Feb 6, 2026
UNLABELLED: Glioblastomas are incurable primary brain tumors that depend on neural-like cellular processes, tumor microtubes (TM), to invade the brain. TMs also interconnect single tumor cells to a communicating multicellular network that resists cur... read more 
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