BACKGROUND: Massive intraoperative bleeding (IBL) in liver transplantation (LT) poses serious risks and strains healthcare resources necessitating better predictive models for risk stratification. As traditional models often fail to capture the compl... read more
Having to control multiple tasks in parallel poses challenges for humans and artificial agents alike. In artificial intelligence, specific forms of reinforcement learning (RL), most notably hierarchical and model-based RL, have shown promising result... read more
BACKGROUND: Coronary revascularization decision-making for patients with coronary artery disease (CAD) can be complex and challenging. Artificial intelligence (AI) has the potential to improve this decision-making by bringing data-driven insights to ... read more
Defining and finalizing Mergers and Acquisitions (M&A) requires complex human skills, which makes it very hard to automatically find the best partner or predict which firms will make a deal. In this work, we propose the MASS algorithm, which adapts a... read more
Proceedings of the National Academy of Sciences of the United States of America
Feb 6, 2026
Symbiotic nutrient exchange between arbuscular mycorrhizal (AM) fungi and their host plants varies widely depending on their physical, chemical, and biological environment. Yet dissecting this context dependency remains challenging because we lack me... read more
Proceedings of the National Academy of Sciences of the United States of America
Feb 6, 2026
Brainstem white matter (WM) bundles are essential conduits for neural signals that modulate homeostasis and consciousness. Their architecture forms the anatomic basis for brainstem connectomics, subcortical circuit models, and deep brain navigation t... read more
Proceedings of the National Academy of Sciences of the United States of America
Feb 6, 2026
Continual learning (CL) enables animals to learn new tasks without erasing prior knowledge. CL in artificial neural networks (NNs) is challenging due to catastrophic forgetting, where new learning degrades performance on older tasks. While various te... read more
Proceedings of the National Academy of Sciences of the United States of America
Feb 6, 2026
Depression is shaped by both genetic and environmental factors, but genome-wide interaction studies (GWIS) often lack power to detect complex gene-environment (G × E) interactions. We applied a forest-based machine learning approach to 38,018 UK Biob... read more
Proceedings of the National Academy of Sciences of the United States of America
Feb 6, 2026
Deciphering the structure of variable sensory input is key to building an accurate model of one's environment. Humans can accumulate evidence from sequences of stimuli to estimate their sensory statistics, predict the timing of upcoming stimuli, but ... read more
Degrons are short protein segments that direct proteins for degradation via the ubiquitin-proteasome system, ensuring the removal of signaling proteins and clearance of misfolded proteins. We have performed a large-scale screen of more than 200,000 3... read more
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