Clinical pharmacology and therapeutics
Feb 6, 2026
Drug-induced QT-interval prolongation, a non-specific biomarker of increased risk for Torsades de Pointes (TdP), is a major safety concern in drug development. While in vitro hERG inhibition assays are required for early-phase screening, pharmacovigi... read more
BACKGROUND: The incidence of thyroid cancer has increased markedly in recent years, largely driven by well-differentiated thyroid carcinoma (WDTC). WDTC is biologically heterogeneous, with generally favorable prognosis but substantial variability in ... read more
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Feb 6, 2026
INTRODUCTION: Accurate assessment of skeletal maturity is essential for orthodontic treatment planning and growth modulation. This study aimed to develop a comprehensive machine learning (ML) model to predict skeletal maturation stages using cervical... read more
As use of artificial intelligence algorithms in clinical practice becomes more commonplace, radiologists may become overconfident in the abilities of these applications or succumb to automation bias. However misplaced confidence in artificial intelli... read more
Age-associated dysbiosis, marked by shifts in the composition of gut microbiota and gut microbiota-derived metabolites (GMDMs), is increasingly implicated in driving systemic low-grade inflammation during aging. The disrupted GMDM pools, including al... read more
An artificial intelligence model that incorporates a range of tumor and patient data proved significantly more accurate in retrospectively predicting breast cancer recurrence than a commonly used genomic test, suggesting that multimodal models could ... read more
Soft actuators possess both active and passive degrees of freedom (DOFs). This paper proposes the concept of using soft actuators to drive rigid-soft coupled single-open-chain (SOC) configurations. Research focuses on the active and passive DOF chara... read more
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.