Polycystic ovary syndrome (PCOS) represents the leading endocrine problem affecting women of reproductive age, leading to serious complications related to reproduction, metabolism, and psychosocial aspects. Nonetheless, due to the heterogeneous natur... read more
European journal of medicinal chemistry
Feb 5, 2026
A machine learning-guided strategy, which integrated unsupervised structural clustering to identify diverse scaffolds for molecular hybridization followed by synergistic QSAR and molecular docking screening, identified lead compound 7. Guided by this... read more
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Feb 5, 2026
Early diagnosis of liver cancer is crucial for developing clinical treatment strategies and improving patient survival rates. However, current diagnostic methods are often invasive, complex, and time-consuming, making them unsuitable for early screen... read more
Analytical methods : advancing methods and applications
Feb 5, 2026
The integrity of competitive athletics is increasingly compromised by sophisticated pharmacologies, rendering traditional sporadic testing of urine and blood insufficient for comprehensive oversight. This critical review examines the emergence of wea... read more
Biomedical materials (Bristol, England)
Feb 5, 2026
Shear stress serves as a key physical stimulus in three-dimensional (3D) cell culture systems, regulating critical physiological processes such as cell alignment, polarity maintenance, and functional maturation. This review systematically analyses 87... read more
Facial plastic surgery & aesthetic medicine
Feb 5, 2026
BACKGROUND: Artificial intelligence (AI) and machine-learning technology are on the rise, including ChatGPT and Google's Gemini, previously known as Bard. While recent studies have begun to explore the role of AI in medicine, there are no studies to ... read more
BACKGROUND: Secondary distribution of HIV self-testing can expand testing among men who have sex with men. A parent quasi-experimental trial found that sexual health influencers (SHIs) identified by a machine-learning model achieved greater peer upta... read more
European heart journal. Digital health
Feb 5, 2026
AIMS: Coronary angiography might contain clinically relevant information, beyond its traditional role in delineating coronary artery disease. We sought to explore the role of deep learning (DL) in detecting right ventricular dysfunction from routinel... read more
PURPOSE: Programmed cell death ligand-1 (PD-L1) is a key prognostic and predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC). This study aimed to develop a machine-learning model using CT-based radiomic features to predict PD-... read more
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