BACKGROUND: Vedolizumab, a monoclonal antibody targeting the α4β7 integrin, offers gut-selective immunosuppression and represents a cornerstone biologic therapy for moderate-to-severe ulcerative colitis (UC). While pivotal randomized controlled trial... read more
The study examines the effect of monetary policy and trade openness on economic growth in the ECOWAS countries. Using panel regression analysis and the Random Forest algorithm from the machine learning technique, the study reveals the existence of a ... read more
Mine explosion-proof diesel engines are critical for underground coal mining, yet the long-term performance degradation of their exhaust systems poses substantial risks to operational safety and environmental compliance-a gap not addressed in short-t... read more
Speed tracking control (STC) and energy saving of an electric vehicle (EV) play a crucial role in the stability and effectiveness of the operating performance of an EV drive system (EVDS). This paper proposes a novel STC and energy saving methodology... read more
Blood cancer originates in the bone marrow and disrupts the body's normal hematopoietic processes. The rapid progression of this disease highlights the need for accurate and sensitive detection to improve treatment outcomes. Here, we present a novel,... read more
In drug discovery and therapeutic research, the prediction of drug-disease associations (DDAs) holds significant scientific and clinical value. Drug molecules exert their effects by precisely identifying disease-related biological targets, systematic... read more
China's national "mass entrepreneurship and innovation" strategy has sparked growing attention toward cultivating entrepreneurial competencies among university students. As a vital resource and interactive platform, social media profoundly shapes the... read more
BackgroundEffective communication and shared decision-making are essential for optimising urological care, making informed decisions, and improving patient outcomes. The integration of artificial intelligence (AI) in urology has the potential to act ... read more
The accurate detection of genetic variants is critical for advancing genomics research and precision medicine. However, this task remains challenging due to pervasive sequencing errors and complex genomic regions. The choice of variant calling softwa... read more
BACKGROUND: Post-operative outcomes of cardiovascular surgery vary greatly among patients for a variety of reasons. While the specific reasons are often multifactorial and complex, certain machine learning methods are promising ways to both estimate ... read more
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