Gastrointestinal (GI) diseases pose significant health risks to humans. To help medical professionals in early GI disease detection and diagnosis through image processing and analysis, this article offers an in-depth exploration of improving GI disea... read more
International journal of pharmaceutics
Feb 5, 2026
This study investigates the use of UV imaging combined with artificial neural networks (ANNs) to estimate the dissolution behaviour of extended-release hydroxypropyl methylcellulose (HPMC) matrix tablets. UV illumination enables the detection of HPMC... read more
The drug development pipeline remains extraordinarily complex, costly, and time-intensive, typically requiring 10-15 years and $2-3 billion per approved drug. This review presents a translational perspective on how artificial intelligence (AI) and ma... read more
Anaesthesia, critical care & pain medicine
Feb 5, 2026
BACKGROUND: Preoperative anaesthetic consultation is essential for perioperative care, involving risk assessment, treatment optimisation, and planning of anaesthetic strategies according to established guidelines. Large language models (LLMs) could o... read more
Clinica chimica acta; international journal of clinical chemistry
Feb 5, 2026
Autoimmune diseases comprise a broad spectrum of disorders in which both the innate and adaptive branches of the immune system malfunction, mistakenly attacking the body's own tissues and organs. This breakdown in self-tolerance is marked by the gene... read more
PURPOSE: Adipose tissue innervation is critical for regulating lipolysis, adipogenesis, and thermogenesis, yet the mechanisms that establish and maintain these neural networks remain poorly understood. Semaphorin 7A (Sema7A), a well-characterized axo... read more
Progress in biophysics and molecular biology
Feb 5, 2026
RNA-small molecule interactions are fundamental to cellular regulation and have emerged as highly attractive therapeutic targets. Despite their potential, discovering RNA-binding small molecules remains challenging due to RNA's intrinsic structural f... read more
Microglial phagocytosis is essential for neurological recovery after intracerebral hemorrhage (ICH). Using single-cell RNA sequencing, we compared microglial responses in murine and human ICH and identified striking species-specific temporal patterns... read more
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