AI Medical Compendium

Machine learning prediction of multiple distinct high-affinity chemotypes for α-synuclein fibrils.

Chemical communications (Cambridge, England) Feb 3, 2026

To identify new ligands for positron emission tomography imaging of α-synuclein aggregates, we developed a machine learning model trained on <300 binding measurements. We used scaffold-guided curation to select a 30 compound prospective set from a 14... read more

Millions Turn to AI Chatbots for Mental Health Support.

JAMA Feb 3, 2026

A multi-view neural framework with attention for epileptic seizure classification.

Journal of neural engineering Feb 3, 2026

Objective. Epilepsy is a chronic brain disorder characterized by recurrent seizures due to abnormal neuronal firing. Electroencephalogram (EEG)-based seizure classification has become an important auxiliary tool in clinical practice. This study aims ... read more

Corrigendum: Machine learning identifies activation of RUNX/AP-1 as drivers of mesenchymal and fibrotic regulatory programs in gastric cancer.

Genome research Feb 3, 2026

spRefine denoises and imputes spatial transcriptomics with a reference-free framework powered by genomic language model.

Genome research Feb 3, 2026

The analysis of spatial transcriptomics is hindered by high noise levels and missing gene measurements, challenges that are further compounded by the higher cost of spatial data compared to traditional single-cell data. To overcome this challenge, we... read more

RetNeXt: A Pretrained Model for Transfer Learning Across the MOF Adsorption Space.

Journal of chemical information and modeling Feb 3, 2026

Because of their ultrahigh porosity and tunable chemistry, metal-organic frameworks (MOFs) have emerged as leading candidates for gas adsorption applications. Nevertheless, their combinatorial nature induces a vast chemical space, challenging traditi... read more

Refined trajectory smoothing and deep learning classification of human sperm motility.

Human reproduction (Oxford, England) Feb 3, 2026

STUDY QUESTION: Can precise trajectory smoothing improve extraction of sperm motility features, and can deep learning on raw trajectory data enable accurate classification of sperm motility patterns? SUMMARY ANSWER: We present an approach that enhanc... read more

TriNet-MTL: A Multi-Branch Deep Learning Framework for Biometric Identification and Cognitive State Inference from Auditory-Evoked EEG.

eNeuro Feb 3, 2026

Auditory-evoked EEG signals contain rich temporal and cognitive features that reflect both the identity of individuals and their neural response to external stimuli. Traditional unimodal approaches often fail to fully leverage this multidimensional i... read more

Identification of cognitive phenotypes in temporal lobe epilepsy and genetic generalized epilepsy using robotic assessment.

Epilepsy & behavior : E&B Feb 3, 2026

BACKGROUND: Cognitive dysfunction is common in people with epilepsy (PWE). Although expectations exist for deficits based on diagnosis, phenotypic variation of cognitive deficits is observed within epilepsy subtypes. Classification by severity and ty... read more

Treating autism with Bumetanide: Identification of responders using Q-Finder machine learning algorithm.

Translational psychiatry Feb 3, 2026

Bumetanide, a specific NKCC1 co-transporter inhibitor, restores deficient GABAergic inhibition implicated in various brain disorders, including Autism Spectrum Disorders (ASD). In keeping with this mechanism, nine successful phase 2 clinical trials, ... read more

Artificial Intelligence Medical Compendium