OBJECTIVES: Artificial intelligence (AI) has shown increasing potential in dental diagnostics, yet its accuracy for binary classification of dental caries across different imaging modalities remains unclear. This study aimed to systematically evaluat... read more
Nuclear morphology encodes rich phenotypic information critical for understanding cellular states, yet its full potential remains untapped in biomedical analysis. This study introduces NuSPIRe, a self-supervised deep learning model designed to analyz... read more
Cancer imaging : the official publication of the International Cancer Imaging Society
Feb 3, 2026
BACKGROUND: Accurate differentiation between luminal A and B subtypes of breast cancer is critical for selecting therapeutic strategies. However, current approaches rely predominantly on invasive biopsy and immunohistochemical (IHC) analysis. Therefo... read more
BACKGROUND: Heat stress (HS) adversely affects poultry health and productivity. Recently, it has been suggested that the gut microbiota may play a role in host resilience to HS, although the details of its mechanism remain unclear. Here, the heat tol... read more
Oral squamous cell carcinoma (OSCC), the most common oral malignancy, requires accurate diagnostic methods for patient stratification and treatment guidance. Exosome-based liquid biopsy represents a promising minimally invasive approach to cancer det... read more
Angewandte Chemie (International ed. in English)
Feb 3, 2026
Na+ ion as charge-balance agent controlling the distribution of framework aluminum atoms in Y-zeolite from 1 to 14 Al atoms (Si/Al = 47-2.4) and the acid strength have been investigated based on DFT computations, descriptors from machine learning, AI... read more
Proteolysis Targeting Chimeras (PROTACs) represent a transformative approach to drug development by leveraging the intracellular ubiquitin-proteasome system (UPS) for the selective degradation of target proteins. A PROTAC molecule comprises three ess... read more
BACKGROUND: Managing stored-grain pests requires new strategies to limit economic and health risks. This study analyses the sublethal effects of the natural compound carlina oxide on Prostephanus truncatus, providing new behavioural insights through ... read more
BACKGROUND: Aspiration causes or aggravates a variety of respiratory diseases. Subjective bedside evaluations of aspiration are limited by poor inter- and intra-rater reliability, while gold standard diagnostic tests for aspiration, such as video flu... read more
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