Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 54,811 to 54,820 of 226,183 articles

Beyond Lipschitz: Ranking Binding Affinity in Hyperbolic Space

bioRxiv Feb 3, 2026
Despite the importance of protein-ligand affinity ranking in drug discovery, existing deep learning models struggle to distinguish hard inactives that are structurally similar to active compounds but biologically inactive. We theoretically show this ... read more 
bioinformatics

Deep-learning-based fMRI decoding of real-world size for hand-held objects

bioRxiv Feb 3, 2026
Real-world object size is a fundamental dimension of visual cognition, supporting effective interaction with the environment and object manipulation. However, neural mechanisms encoding size have largely been inferred from extreme size comparisons, l... read more 
neuroscience

Domain Adaptation Enables Cross-site Classification of First-episode Schizophrenia from Multimodal Neuroimaging Data

bioRxiv Feb 3, 2026
Identifying robust neuroimaging markers associated with schizophrenia is essential for advancing research and informing clinical understanding. However, a major obstacle to clinical translation is the limited ability of neuroimaging-based classificat... read more 
neuroscience

Transformer-Based Phenotyping of Rice Root Aerenchyma Across Environments Enables Climate-Smart Rice Selection

bioRxiv Feb 3, 2026
Quantification of root anatomical traits such as cortical aerenchyma is key to understanding rice adaptation to diverse water regimes. Recently, the role of aerenchyma in regulating methane emissions has been demonstrated, making it a target for clim... read more 
physiology

Microplastics drive both linear and threshold-type shifts in soil multifunctionality along concentration gradients

bioRxiv Feb 3, 2026
Microplastics are increasingly recognized as emerging contaminants in terrestrial ecosystems, yet their mechanistic impacts on soil multifunctionality remain poorly understood. Here, we evaluated the influence of two microplastic types, polyethylene ... read more 
ecology

Brainstem neurons coordinate the bladder and urethral sphincter for urination

bioRxiv Feb 3, 2026
Urination, a vital and conserved process of emptying urine from the urinary bladder in mammals, requires precise coordination between the bladder and external urethral sphincter (EUS) that is tightly controlled by a complex neural network. However, t... read more 
neuroscience

Automated Segmentation of Kidney Nephron Structures by Deep Learning Models on Label-free Autofluorescence Microscopy for Spatial Multi-omics Data Acquisition and Mining

bioRxiv Feb 3, 2026
Automated spatial segmentation models can enrich spatio-molecular omics analyses by providing a link to relevant biological structures. We developed segmentation models that use label-free autofluorescence (AF) microscopy to recognize multicellular f... read more 
bioinformatics

Organellomics: AI-driven deep organellar phenotyping reveals novel ALS mechanisms in human neurons

bioRxiv Feb 2, 2026
Systematic assessment of organelle architectures, termed the organellome, offers valuable insights into cellular states and pathomechanisms, but remains largely uncharted. Here, we present a deep phenotypic learning based on vision transformers, resu... read more 
systems biology

MLMarker: A machine learning framework for tissue inference and biomarker discovery

bioRxiv Feb 2, 2026
MLMarker is a machine learning tool that computes continuous tissue similarity scores for proteomics data, addressing the challenge of interpreting complex or sparse datasets. Trained on 34 healthy tissues, its Random Forest model generates probabili... read more 
bioinformatics

Set-up, validation, evaluation, and cost-benefit analysis of an AI-assisted assessment of responsible research practices in a sample of life science publications

bioRxiv Feb 2, 2026
The (semi-)automated screening of publications for diverse quality and transparency criteria is at the core of systematic literature assessment. Typically, the assessment process involves two initial reviewers and one additional reviewer for cases th... read more 
scientific communication and education
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