Early and accurate diagnosis of Alzheimer's disease (AD) remains a critical challenge in neuroimaging-based clinical decision support systems. In this work, we propose a novel hybrid deep learning framework that integrates Topological Data Analysis (... read more
Prediction sets can wrap around any ML model to cover unknown test outcomes with a guaranteed probability. Yet, it remains unclear how to use them optimally for downstream decision-making. Here, we propose a decision-theoretic framework that seeks to... read more
Handheld Optical Coherence Tomography Angiography (OCTA) enables noninvasive retinal imaging in uncooperative or pediatric subjects, but is highly susceptible to motion artifacts that severely degrade volumetric image quality. Sudden motion during 3D... read more
Ultrasound imaging is the primary diagnostic modality for detecting Gallbladder diseases due to its non-invasive nature, affordability, and wide accessibility. However, the low resolution and speckle noise inherent to ultrasound images hinder diagnos... read more
Childhood anemia remains a major public health challenge in Nepal and is associated with impaired growth, cognition, and increased morbidity. Using World Health Organization hemoglobin thresholds, we defined anemia status for children aged 6-59 month... read more
The diagnosis of thyroid nodule cancers commonly utilizes ultrasound images. Several studies showed that deep learning algorithms designed to classify benign and malignant thyroid nodules could match radiologists' performance. However, data availabil... read more
Vision-language models (VLMs) extend large language models (LLMs) with vision encoders, enabling text generation conditioned on both images and text. However, this multimodal integration expands the attack surface by exposing the model to image-based... read more
Large Vision-Language Models (LVLMs) can reason effectively from image-text inputs and perform well in various multimodal tasks. Despite this success, they are affected by language priors and often produce hallucinations. Hallucinations denote genera... read more
Repertoire-level analysis of T cell receptors offers a biologically grounded signal for disease detection and immune monitoring, yet practical deployment is impeded by label sparsity, cohort heterogeneity, and the computational burden of adapting lar... read more
Ultrasound (US) imaging exhibits substantial heterogeneity across anatomical structures and acquisition protocols, posing significant challenges to the development of generalizable analysis models. Most existing methods are task-specific, limiting th... read more
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